A Phase II trial of neoadjuvant chemotherapy with S-1 and fractional cisplatin for locally advanced gastric cancer
- Conditions
- Gastric cancer
- Registration Number
- JPRN-UMIN000001777
- Lead Sponsor
- Division of Biological Regulation and Oncology, Department of Surgery, Graduate School of Medicine, Tohoku University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Sex
- All
- Target Recruitment
- 25
Not provided
Exclusion criteria 1)Fresh bleeding from the tumor 2)Paralysis of intestine or ileus 3)Diarrhea(watery stool) 4) Synchronous multicancer 5) infection 6) Interstitial pneumonitis or fibroid lung 7) a large amount of pleural effusion or ascites 8) Jaundice 9)Uncontrollable diabetes mellitus, 10) heart failure requiring the treatment, myocardial infarction within 6 months, uncontrolled arrhythmia or angina 11)Patients pregnant or in lactation, or wish to become pregnant during this study. Male patients who intend to make someone pregnant during this study 12)Patient who has experienced serious drug allergy in the past 13)Patient who is judged to be inappropriate for this study by the principal investigator or the doctors in charge
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Response rate, pathological response
- Secondary Outcome Measures
Name Time Method Over all survival , relapse free survival, curative resection rate, operative complication rate, adverse event