evaluation of usg guided bilateral tap block versus intraperitoneal instillation of levobupivacaine for post operative analgesia in laparoscopic abdominal surgeries

Not yet recruiting

• Conditions: Unspecified chronic bronchitis,

• Registration Number: CTRI/2025/03/082278
• Lead Sponsor: GANDHI MEDICAL COLLEGE

Brief Summary

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|·       Abdominal laproscopic surgeries are most commonly associated with moderate to severe post operative pain .Pain is because of incisional site pain (somatic) and visecral (deep intrabdominal) . Visceral pain after laparoscopic surgery can be triggered by traction of peritoneum or by irritation of the diaphragm following surgical manipulation, intraoperative gas insufflation and post operative gas retention.

·       Acute postoperative pain is a complex physiological  reaction, and it is detrimental because it increases the  patient’s discomfort and may transform into chronic pain.  Optimal postoperative analgesia is important to prevent  negative outcomes.

·       In addition to the parental opioids and NSAIDS, various other method use for post operative analgesia are infilteration of local anaesthetic agent, dermal patch, patient controlled analgesia and epidural catheter etc.

·       Instillation of local anaesthesia intraperitoneally  around the operative site is used as an analgesic technique on the assumption that conduction from visceral sites is obstructed and may lessen the intensity of referred pain to the shoulder (C3 and C4) which results from irritation of diaphragmatic innervation. i.e. phrenic nerve (C3, C4, C5) and diaphragmatic stretching due to gaseous retention in the postoperative period.

·       Intraperitoneal instillation of non steroidal anti inflammatory drug (NSAIDS) and narcotics, gas drainage, intraperitoneal  local anesthetic drug alone or with opioids and alpha 2 agonist drugs such as clonidine and dexmedetomidine before the end of the surgery by the surgeon is routinely performed before trocar removal at the surgical site can decrease the postoperative pain after laparoscopic surgery.

·       The Transverse abdominal plane block is relatively newer and a novel approach of injecting local anaesthetic agent the plane between the internal oblique and transversus abdominis muscle and thus giving pain relief.

·       The TAP block can provide excellent analgesia to the skin and muscles of the anterior abdominal wall following the inguinal hernia repair, appendectomy, radical prostatectomy, abdominoplasty, renal transplantation, large bowel resection, cesarean section, laproscopic cholecystectomy and Iliac crest bone grafting.

 ·       We intend to assess the analgesic efficacy of ultrasound guided bilateral TAP block versus intraperitoneal instillation of levobupivacaine in patients undergoing laparoscopic abdominal surgeries.

Detailed Description

Not available

Study Timeline

• Study Start: 2025-03-23
• Last Update Posted: 2025-12-03

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• 1.Patients of ASA grade.
• I ,II 2.Age group 18-60 years of either sex. 3.All patients scheduled for elective laparoscopic abdominal surgery.

Exclusion Criteria

• 1Patient refusal or not giving consent.
• 2Pregnancy 3Patient with coagulopathies 4Seizure disorder 5ASA grade III and above 6Patient on anticoagulants •Patient consuming adrenoreceptors agonist or antagonist •History of drug allergy levobupivacaine •Patients with history of cardiac, respiratory, renal or hepatic failure.
• •Difficult Airway.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
TAP block is better that usg guided intraperitoneal instillation of levobupivacaine for post op analgesia	10 weeks

Secondary Outcome Measures

Name	Time	Method
to assess the total resue analgesia consumptiion in 24hrs. to estimate the duration of analgesia after tap block	8 weeks

Trial Locations

Locations (1)

GANDHI MEDICAL COLLEGE; 🇮🇳 Bhopal, MADHYA PRADESH, India

GANDHI MEDICAL COLLEGE

🇮🇳Bhopal, MADHYA PRADESH, India

DR AISHWARYA SHRIVASTAVA

Principal investigator

08319657804

waryaish26@gmail.com