An Acupuncture Study for People At High Risk for Sepsis

Phase 2

Recruiting

• Conditions: Sepsis
• Interventions: Procedure: Acupuncture; Other: Sham Acupuncture

• Registration Number: NCT06344819
• Lead Sponsor: Memorial Sloan Kettering Cancer Center

Brief Summary

Researchers think acupuncture may improve outcomes for participants with sepsis, based on laboratory studies and previous studies in people with sepsis. The purpose of this study to see whether real acupuncture can improve outcomes for participants with sepsis when compared to sham acupuncture. Sham acupuncture is performed the same way as real acupuncture but will use different needles and target different sites or places on the body than real acupuncture.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-03-20
• Study First Submitted: 2024-03-21
• Study First Submitted QC: 2024-03-27
• Study First Posted: 2024-04-03
• Status Verified: 2025-05
• Last Update Submitted: 2025-05-19
• Last Update Posted: 2025-05-22
• Primary Completion: 2028-03-20
• Study Completion: 2028-03-20

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 78

Inclusion Criteria

• Age 18 or older
• Having MSK sepsis order-set placed within the previous 48 hours

Exclusion Criteria

• The study Principal Investigator will review the medical record again prior to enrollment to exclude non-sepsis patients (Even though the placement of sepsis order set already screens out such patients, subsequent clinical development after sepsis order set placement may generate new information that deems the patient not septic.)
• Admitted to ICU before being approached for consenting
• Having an implanted medical device, such as a pacemaker or implantable cardioverter-defibrillator (ICD), with which electroacupuncture
• Unable to obtain informed consent due to a participant's mental status and absence of an individual authorized to give consent on the participant's behalf
• The patient is on an interventional clinical trial and its Principal Investigator does not give approval to enrollment to this study (e.g. genomic profiling, biospecimen, or observational studies do not require PI approval).

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Acupuncture	Acupuncture	-
Sham Acupuncture	Sham Acupuncture	-

Primary Outcome Measures

Name	Time	Method
Number of participants recruited compared to the number of participants who complete study treatment.	Up to 2 years	To assess the feasibility of conducting a randomized controlled trial of acupuncture in hospitalized patients who are at risk for sepsis.

Trial Locations

Locations (1)

Memorial Sloan Kettering Cancer Center; 🇺🇸 New York, New York, United States