Study Of Anorectal Manometry Profile Of Patients With Functional Constipation Or Constipation Predominant Irritable Bowel Syndrome In A Tertiary Care Center Of Eastern India
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Differences in anorectal manometry parameters between functional constipation and constipation predominant irritable bowel syndrome group.
Study Overview
Brief Summary
Purpose of the study to evaluate the anorectal manometry profile of patients with functional constipation or constipation predominant irritable bowel syndrome. Initially basic details will be taken, question related to onset of symptoms, progression of symptoms and other relevant questions on present, past and personal details will be asked. Those who will fulfill inclusion criteria will be included in study. Subjects will be asked about their blood test reports and radiological investigations. Subject will undergo digital rectal examination, ultrasound of whole abdomen, colonoscopy/ sigmoidoscopy and anorectal manometry. After that difference in anorectal manometry between functional constipation and constipation predominant irritable bowel syndrome will be evaluated.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 18.00 Year(s) to 65.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Patient of either gender and age group above 18 years and less than 65 years, chronic constipation of more than 6-month duration defined according to ROME IV criteria (with Bristol stool form I to III) and fulfilling the ROME IV criteria of Functional constipation or constipation-predominant irritable bowel syndrome.
- •2.Normal sigmoidoscopy/colonoscopy.
Exclusion Criteria
- •Patients having Constipation due to secondary causes like mechanical obstruction and drugs.
- •Patients having diabetes mellitus (HbA1c more than 7.5) Patients having thyroid disease (TSH value more than 7) Patients having decompensate liver disease.
- •Patients having Stage 3 and above Chronic kidney disease Patients having history of abdominal surgery except cholecystectomy and appendectomy Patients having history of Gynecological surgery Patients not giving consent.
Outcomes
Primary Outcomes
Differences in anorectal manometry parameters between functional constipation and constipation predominant irritable bowel syndrome group.
Time Frame: At end of study
Secondary Outcomes
- Proportion of patients with dyssynergia.
Investigators
Probal Saha
IPGMER AND SSKMH