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Clinical study on the effect of treatment of Amvata ( all joint pain) and effect of regular purgation ,oral intake of medicated Ghrita and Amritadi guggulu(oral medication) in the management of Amavata(RA)

Phase 3
Completed
Conditions
Diagnosed patients of Amavata on the basis of clinical features as per Classical Ayurveda textbook and according to criteria of ACR
Registration Number
CTRI/2018/03/012511
Lead Sponsor
National Institute Of Ayurveda
Brief Summary

Rheumatoid Arthritis is on of the common debilitating disease it is categorized under autoimmune disorder along with locomotor  system , it is also affecting the cardio vascular , nervous respiratory and excretory system  of the body. Rheumatid Arthritis sometimes  progress relentlessy to joint destruction  and crippling .Disease modifying anti rheumatic drug (DMARD) are associated with several adverse effects   In *Ayurveda* based on clinical manifestations there is a close resemblance between *Amavata* and Rheumatoid Arthritis.Amavata described in Ayurveda,which is characterized with Angamarda (Bodyache),Aruchi (Anorexia),Trishna(thirst),Alasya(Lethargy),Gaurav (heaviness in the body),Jwara(Fever),Apaka (indigestion),Shunata (Swelling),Sandhishula (pain in joints),Stambha(Stiffness) etc  *Ayurveda* though its holistic approach and radical treatment like P*anchakarma* which corrects the basic pathology by eliminating the chief causative factors . P*anchakarma* not only cures the disease but also maintains total health of the body . The study was planned The study was  conducted on 90 clinically diagnosed cases of Amavata from OPD and IPD of dept.P*anchakarma* National Institute of Ayurveda, Patients were randomly divided into three group viz  group A Sequential employment of langhana, valuka  swedana,tikta katu deepana, virechana karma, snehapana, Basti karma in 30 patients group  B 30 patients were  subjected to langhana(laghu bhojana), valuka swedana, tikta katu deepana(Musta,Shunthi, Indrayava and Guduchi sama bhaga churna) for 7 days followed by Nitya virechana with 10 ml Eranda Taila for 7 days followed by snehapana with indukanta Ghrita for 7 days followed by oral administration of Amritadi guggulu (500 mg tab) 2 tab three times a day for 15 days with luke warm water. Group c  30 patients were  subjected to langhana(laghu bhojana), valuka swedana, tikta katu deepana(Musta,Shunthi, Indrayava and Guduchi sama bhaga churna) for 7 days  with oral administration of Amritadi guggulu (500 mg tab) 2 tab three times a day for 30 days with  warm water Written consent was taken from patient before starting trial Assisment was done before and after treatment and after follow up period.

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
90
Inclusion Criteria

Prediagnosed case of Amavata (RA) with chronicity upto 10 year Patient fit for Valuka Swedana Virechana Karma Snehapana and Basti Karma.

Exclusion Criteria

Age below 16 years and above 60 years of either sex Chronicity more than 10 years Patients with severe crippling deformities extremely reduced joint space bone deformity Any associated cardiac disease pulmonary tuberculosis DM Malignant hypertension renal function impairment Patient not fit for Valuka Swedana Virechan karma snehpan and Basti Karma.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Improvement in subjective and objective parameter3 months
Secondary Outcome Measures
NameTimeMethod
To find out the comparative efficacy of the treatment in different groups3 months

Trial Locations

Locations (1)

National Institute of Ayurveda Jaipur

🇮🇳

Jaipur, RAJASTHAN, India

National Institute of Ayurveda Jaipur
🇮🇳Jaipur, RAJASTHAN, India
Ujwala Hivale
Principal investigator
9887507329
ujwala.hivale27@gmail.com

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