Comparison of administrative methods of terlipressin for esophageal variceal bleeding
- Conditions
- Diseases of the digestive system
- Registration Number
- KCT0006107
- Lead Sponsor
- Korea University Ansan Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 126
? Age of 25-75 years
? patients with liver cirrhosis
? the cases with active bleeding or suspected stigma on esophageal varix
? If the selection criteria are not satisfied
? Those with hypersensitivity to terlipressin or contraindications such as ischemic heart disease.
? Gastric variceal bleeding (fundal gastric variceal bleeding, i.e., IGV or GOV2 and the bleeding point is in the stomach and bottom), variceal bleeding on the esophago-gastric junction can be registered.
? When endoscopic variceal obturation (EVO) is required
? When radiological intervention such as BRTO (balloon occluded retrograde transvenous variceal obliteration) or TIPS (transjugular intrahepatic portosystemic shunt) is required
? When compression hemostasis using balloons such as SB tube is necessary
? Those whose vital signs are unstable and unable to perform emergency endoscopy within 24 hours
? Hepatocellular carcinoma exceeding the Milan standard
? Untreated malignant tumor
? Hepatic encephalopathy of stage 3 or higher
? Those who have undergone treatment for esophageal varices within the last 4 weeks
? HIV-infected patients
? Pregnant women, nursing women, and women of childbearing age who do not have the will of contraception.
? Those who do not have the ability to sign the consent form
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Treatment success rate in both groups
- Secondary Outcome Measures
Name Time Method Economic evaluation;Severity and incidence of adverse drug reactions;Survival of cirrhotic patients with variceal bleeding;occurrence of cirrhosis complications