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Influence of Umbilical Cord Clamping Time in the Newborn

Not Applicable
Completed
Conditions
Anemia Neonatal
Polycythemia Secondary
Hyperbilirubinemia, Neonatal
Registration Number
NCT03624335
Lead Sponsor
Pascual Gregori Roig
Brief Summary

This study compares two umbilical cord clamping times; the early one, up to a minute (ECC) and the late or delayed one, when the cord stop beating (DCC). The additional blood volume delivered to the newborn from the placenta - placental transference - by delaying umbilical cord ligation, increases the contribution of neonatal iron with increased iron stores in the infant, without increasing neonatal morbidity.

Detailed Description

It is an intervention study without drugs administration with a longitudinal, prospective comparison and correlational design.

Patients are recruited by simple random sampling to one of the two intervention groups:

Group 1-ECC: Early clamping of the umbilical cord (before the first minute of life).

Group 2-DCC: Delayed clamping of the umbilical cord (when it stops beating).

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
195
Inclusion Criteria
  • neonates with a gestational age of 35 to 42 weeks and born through normal vaginal delivery.
Exclusion Criteria
  • monochorionic multiples
  • incarcerated mothers
  • placenta previa
  • concern for abruptions
  • Rh sensitization
  • hydrops
  • congenital anomalies
  • the obstetrician declining to perform the intervention

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
haemoglobin28 days

haemoglobin level

haematocrit28 days

haematocrit level

Secondary Outcome Measures
NameTimeMethod
serum ferritin28days

serum ferritin level

bilirubin28days

bilirubin level

Trial Locations

Locations (1)

Hospital Universitario de La Plana

🇪🇸

Villarreal, Castellón, Spain

Hospital Universitario de La Plana
🇪🇸Villarreal, Castellón, Spain

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