Efficacy of Magnesium Sulfate as an Adjuvant in Erector Spinae Plane Block as an Anesthetic Post Operative After Modified Radical Mastectomy

Early Phase 1

Not yet recruiting

• Conditions: ESPB, Mg Sulfate,Post Mastectomy
• Interventions: Drug: Magnesium sulfate in erector spinae plane block

• Registration Number: NCT05976464
• Lead Sponsor: Assiut University

Brief Summary

efficacy of magnesium sulfate as an adjuvant in erector spinae plane block as an anesthetic post-operative after modified radical mastectomy

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-07-13
• Study First Submitted QC: 2023-07-27
• Study First Posted: 2023-08-04
• Status Verified: 2024-03
• Study Start: 2024-03-01
• Last Update Submitted: 2024-03-01
• Last Update Posted: 2024-03-04
• Primary Completion: 2024-10-01
• Study Completion: 2024-12-15

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

• 1. ASA I-II. 2. Female patients aged 18-65 years. 3. Scheduled for a modified radical mastectomy with axillary dissection for breast cancer.

Exclusion Criteria

1. ASA < II.

2. more than 65 years old

3. Patients with known allergies to the study drugs

4. Skin infection at the site of needle puncture.

5. Coagulopathy

6. Drug or as that would interfere with perception and assessment of pain. 6. Uncooperative patients.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
erector spinae plane block	Magnesium sulfate in erector spinae plane block	Ultrasound-guided Erector spinae plane (ESP) block will be done with the patient in a sitting position depending on the surgical site (lt. or Rt.) ESP block will be given using high-frequency linear u/s transducer, the probe is placed in longitudinal orientation lateral to the thoracic third and sixth spinous process, the erector spinae muscle, is identified from the surface, we will deposit 20 ml of 0.25% levobupivacaine into interfacial plane below erector spinae muscle.
magnesium sulfate as an adjuvant in erector spinae plane block	Magnesium sulfate in erector spinae plane block	Ultrasound-guided Erector spinae plane (ESP) block will be done with the patient in a sitting position depending on surgical site (lt. or Rt.) ESP block will be given using high-frequency linear u/s transducer, the probe is placed in longitudinal orientation lateral to the thoracic third and sixth spinous process, the erector spinae muscle, is identified from the surface, we will deposit 20 ml of 0.25% levobupivacaine and magnesium sulfate into interfacial plane below erector spinae muscle.

Primary Outcome Measures

Name	Time	Method
- The primary outcome measure in this study will be the total dose of morphine consumption during the 24 hour Postoperatively.	Up to 24 hour