Efficacy of Magnesium Sulfate as an Adjuvant to Local Anesthetic in Erector Spinae Plane Block for Post-operative Analgesia After Modified Radical Mastectomy
试验速览
- 阶段
- 早期 1 期
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- - The primary outcome measure in this study will be the total dose of morphine consumption during the 24 hour Postoperatively.
研究概览
简要总结
efficacy of magnesium sulfate as an adjuvant in erector spinae plane block as an anesthetic post-operative after modified radical mastectomy
详细描述
magnesium sulphate as an adjuvant to local anesthetic in erector spinae plane block compared to local anesthetic only in erector spinae plane block
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •1. ASA I-II.
- •Female patients aged 18-65 years.
- •Scheduled for a modified radical mastectomy with axillary dissection for breast cancer.
排除标准
- •more than 65 years old
- •Patients with known allergies to the study drugs
- •Skin infection at the site of needle puncture.
- •Coagulopathy
- •5. Drug or as that would interfere with perception and assessment of pain.
- •Uncooperative patients.
研究组 & 干预措施
magnesium sulphate as an adjuvant to local anesthetic in erector spinae plane block
Ultrasound-guided Erector spinae plane (ESP) block will be done with the patient in a sitting position depending on the surgical site (lt. or Rt.) ESP block will be given using high-frequency linear u/s transducer, the probe is placed in longitudinal orientation lateral to the thoracic third and sixth spinous process, the erector spinae muscle, is identified from the surface, we will deposit 20 ml of 0.25% levobupivacaine into interfacial plane below erector spinae muscle.
干预措施: Magnesium sulfate in erector spinae plane block (Drug)
local anesthetic only in erector spinae plane block
Ultrasound-guided Erector spinae plane (ESP) block will be done with the patient in a sitting position depending on surgical site (lt. or Rt.) ESP block will be given using high-frequency linear u/s transducer, the probe is placed in longitudinal orientation lateral to the thoracic third and sixth spinous process, the erector spinae muscle, is identified from the surface, we will deposit 20 ml of 0.25% levobupivacaine and magnesium sulfate into interfacial plane below erector spinae muscle.
干预措施: Magnesium sulfate in erector spinae plane block (Drug)
结局指标
主要结局
- The primary outcome measure in this study will be the total dose of morphine consumption during the 24 hour Postoperatively.
时间窗: Up to 24 hour
次要结局
未报告次要终点
研究者
Doha Mohamed Ahmed, MD
Principal investigator
Assiut University