Cord Clamping Study - Mpongwe (Zambia).
Completed
- Conditions
- The study takes place in Mpongwe District, a rural region of the Copperbelt Province in Zambia, approximately 1000m above sea level. Malaria transmission in this area is holoendemic. The rainy season, which is associated with peak malaria transmission, occurs from November to April.
- Registration Number
- NL-OMON25019
- Lead Sponsor
- /A
- Brief Summary
1. Trop Med Int Health. 2007 May;12(5):603-16. <br> <br><br> 2. van Rheenen P, Brabin BJ. Late umbilical cord clamping as an intervention for reducing iron deficiency anaemia in term infants in developing and industrialised countries: a systematic review. Ann.Trop.Paediatr. 2004;24:3-16.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 91
Inclusion Criteria
Full term pregnant women delivering in Mpongwe Mission Hospital are candidates for inclusion in the study.
Exclusion Criteria
1. Twin pregnancy;
2. History of post partum haemorrhage (PPH) > 500 ml;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary endpoints with respect to haematological status are the post-treatment Hb level in relation to pre-treatment values and the proportion of non-anaemic infants at respectively two, four and six months after birth.
- Secondary Outcome Measures
Name Time Method Secondary outcome measures include possible side effects of DCC in infants (PCV changes 1 day postpartum; clinical signs of hyperviscosity syndrome and hyperbilirubinaemia) and mothers (Hb level one day after delivery in relation to antenatal values).