ITMCTR1900002608尚未招募4 期
Effect of Shenfu injection on hemodynamics and clinical efficacy in patients with cardiogenic shock in acute decompensation of chronic heart failure due to coronary heart disease: a multicenter, randomized, double-blinded, parallel placebo-controlled trial
The First Affiliated Hospital of Guangzhou University of Chinese Medicine0 个研究点开始时间: 待定最近更新:
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional study
入排标准
- 年龄范围
- 40 至 80（—）
- 性别
- All
入选标准
- •1. Aged 40 and 80 years;
- •2. Meet the diagnostic criteria of coronary heart disease;
- •3. Meet the diagnostic criteria of acute decompensation of chronic heart failure;
- •4. Meet the diagnostic criteria of cardiogenic shock;
- •5. NYHA classification between III to IV;
- •6. Under the use of norepinephrine, PiCCO showed that MAP>65mmHg, but GEF<25% or CI<3.0L/min/m2, while PVPI<1.2;
- •7. Voluntarily signed the written informed consent form.
排除标准
- •1. Patients with chronic heart failure who are not due to coronary heart disease;
- •2. Patients with any of the following diseases:
- •(1) Acute myocarditis;
- •(2) Hypertrophic obstructive cardiomyopathy;
- •(3) Uncontrolled malignant arrhythmias;
- •(4) Severe valvular heart disease requiring surgical treatment;
- •(5) Uncontrolled blood pressure ( SBP>=180mmHg and/or DBP>=110mmHg );
- •(6) Pulmonary artery embolism;
- •(7) Other diseases that may affect the evaluation of the efficacy and safety of experimental drugs;
- •3. Patients using intra-aortic balloon counterpulsation;
- •4. Aggravation of heart failure caused by digitalis poisoning;
- •5. Diabetic patients with poor blood glucose control within 24 hours before randomization;
- •6. Accompany by severe primary diseases in liver, renel, hematopoietic system, etc. Or severe disfunction of liver or renel;
- •7. Pregnant or lactating women;
- •8. Drug dependence or mental illness;
- •9. Participating in other clinical trials within nearly three month;
- •10. Allergy to Shenfu injection, or allergic constitution;
- •11. To be judged by the researchers that the patient is not appropriate to take part in the clinical trial.
研究者
相似试验
尚未招募
不适用
Effects of early used Shenfu injection on hemodynamics in patients with sepsis: a multicenter, randomized, controlled trialSepsisITMCTR2200006148Zhongnan Hospital of Wuhan University
Unknown
2 期
Shenfu Injection Improves Arterial Vascular ReactivityShenfuVascular ReactivitySeptic ShockNCT03749525Jianfeng Xie26
Unknown
4 期
Randomized Evaluation of Shenfu Injection to Reduce Myocardial InjuryMyocardial InfarctionNCT04493840Beijing Anzhen Hospital326
尚未招募
不适用
Effect of acupuncture on the hemodynamic system in meHealthy subjectsJPRN-UMIN000037973Meiji University of Integrative Medicine30
招募中
1 期
Effect of Shenfu Injection on Antishock and Postoperative Cognitive Impair in Patients with Hemorrhagic Shockpostoperative outcomesITMCTR2100005196affiliated hospital of shandong university of traditional Chinese medicine