Enteral protein delivery in Australia and New Zealand critically ill adults.

Not Applicable

Completed

• Conditions: Critical Illness; Diet and Nutrition - Other diet and nutrition disorders; Public Health - Health service research

• Registration Number: ACTRN12620000006943
• Lead Sponsor: Intensive Care Research, Royal Adelaide Hospital.

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-01-08
• Study Completion: 2020-08-28
• Last Update Posted: 9 August 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 119

Inclusion Criteria

1. Aged 18 years or older.
2. Receiving invasive mechanical ventilation.
3. About to commence enteral nutrition (EN) or EN commenced within the preceding 12 hours.

Exclusion Criteria

1. Expected to be receiving oral nutrition within 24 hours of inclusion.
2. Have received EN or parenteral nutrition (PN) for >12 hours in the ICU admission.
3. Death is deemed to be imminent or inevitable during this admission and either the attending doctor, patient or substitute decision maker is not committed to active treatment
4. The patient has an underlying disease that makes survival to 90 days unlikely
5. The patient has a condition in which the treating clinician believes that administration of a very large or small amount of protein (e.g. large burn injury or urea cycle disorder respectively) is indicated.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mean daily protein delivered from enteral nutrition alone (g/kg Ideal Body Weight/day). Assessed from medical records.[Up to 28 days of ICU admission from the time of study enrolment.]

Secondary Outcome Measures

Name	Time	Method
Mean daily protein delivered from all sources (Enteral Nutrition, Parenteral Nutrition) (g/kg Ideal Body Weight/day). Assessed from medical records.[Up to 28 days of ICU admission from the time of study enrolment.];Mean daily protein prescription (g/kg Ideal Body Weight/day). Assessed from medical records.[Up to 28 days of ICU admission from the time of study enrolment.];Mean daily volume of EN delivered (ml/day). Assessed from medical records.[Up to 28 days of ICU admission from the time of study enrolment.];Mean daily calorie delivery (kcal/kg Ideal Body Weight/day). Assessed from medical records.[Up to 28 days of ICU admission from the time of study enrolment.];Mean Gastric Residual Volume discarded in 24 hours (ml). Assessed from medical records.[Up to 28 days of ICU admission from the time of study enrolment.]