NCT01028547已完成不适用
Antiemetic Efficacy and Safety of Dexamethasone in Patients Undergoing Caesarean Sections at Mulago Hospital
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 250
- 试验地点
- 1
- 主要终点
- presence of post nausea and or vomiting
研究概览
简要总结
This is a randomised controlled double blinded clinical trial to determine the antiemetic efficacy and safety of either 8 mg of dexamethasone or normal saline (placebo) given 1 hour before induction of either spinal or general anaesthesia in 2 arms (of 150 each).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •all woman above 18 years old presenting for obstetric surgery and have consented to study.
排除标准
- •refusal/unable to consent,
- •younger than 18 years old,
- •hypertensive,
- •diabetic,
- •preeclamptic,
- •ASAIIIE plus.
研究组 & 干预措施
dexamethasone 8mg
Active Comparator
干预措施: dexamethasone (Drug)
normal saline
Placebo Comparator
干预措施: normal saline (Other)
结局指标
主要结局
presence of post nausea and or vomiting
时间窗: 24 hours
次要结局
- perianal itching(24 hours)
- hyperglycemia(24 hours)
- hypertension(24 hours)
研究者
研究点 (1)
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