Cross-sectional Examination of the Reliability of Oral Implants

Completed

• Conditions: Periimplantitis

• Registration Number: NCT04690621
• Lead Sponsor: German Association of Oral Implantology e. V.

Brief Summary

Aim of the multi centrical, cross-sectional study is the registration of the prevalence and incidence of mucositis and periimplantitis.

Detailed Description

Aim of the multi centrical, cross-sectional study is the registration of the prevalence and incidence of mucositis and periimplantitis. Additional clinical examination of the tolerance of titanium using cytosine analysis of periimplant sulcus smear and of blood lymphocytes on titanium plates in vitro. In total 10 centers will examine clinical, genetic and microbiological parameters in 200 patients during 12 months.

Study hypothesis: The incidence of mucositis and periimplantitis during a time period of 10 years in patients is less than 30%

Study Timeline

• Status Verified: 2012-06
• Study Start: 2012-07-01
• Primary Completion: 2013-02-20
• Study Completion: 2013-08-07
• Study First Submitted: 2020-12-20
• Study First Submitted QC: 2020-12-29
• Last Update Submitted: 2020-12-29
• Study First Posted: 2020-12-30
• Last Update Posted: 2020-12-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 192

Inclusion Criteria

• Patients with oral implants inserted after 01.04.2002
• Periodical recall

Exclusion Criteria

• No other titanium implants inside the body

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
IL-1ß	6 month	Interleucin 1 beta in peripheral blood

Secondary Outcome Measures

Name	Time	Method
MMP-8	6 month	Metallomatrixproteinase-8 in Periodontal Sulcus Fluid
BOP	6 months	Bleeding on probing
PD	6 months	Probing Depth

Trial Locations

Locations (1)

Gerhard Iglhaut; 🇩🇪 Memmingen, Germany