Role of Ayurvedic medicine in the Management of Psoriasis (skin disease).
- Conditions
- Psoriasis vulgaris. Ayurveda Condition: SIDHMAH,
- Registration Number
- CTRI/2021/03/032363
- Lead Sponsor
- National Institute of Ayurveda Jaipur
- Brief Summary
Disease reference:- *Sidhma Kushtha* mentioned in *Charak Samhita Nidana*(5/6)and *Chikitsa sthan* (7/19)
शà¥à¤µà¥‡à¤¤à¤‚ तामà¥à¤°à¤‚ तनॠच यदà¥à¤°à¤œà¥‹ घृषà¥à¤Ÿà¤‚ विमà¥à¤žà¥à¤šà¤¤à¤¿| अलाबूपà¥à¤·à¥à¤ªà¤µà¤°à¥à¤£à¤‚ ततॠसिधà¥à¤®à¤‚ पà¥à¤°à¤¾à¤¯à¥‡à¤£ चोरसि|| (Ch. Chi. 7/19)
In *Sushrut Samhita Nidana Sthana* (5/12)
In *Ashtang Hridaya Nidana Sthana* (14/22)
Drug reference :- 1*. Kushthadalan Ras: Raskamdhenu* *41/330*
2.*Somraji Taila: Chakradatta Kushthachikitsa* 163,164,165
3.*Darvyadi Kwath: Astang Hridaya Chikitsa Sthan-Kushthachikitsa* 19/37
**Need of Study: -**
1. The worldwide burden of Psoriasis is 2%, and the prevalence of Psoriasis in India ranges from 0.44% to 2.8%.
2. Now a days Psoriasis became a most common type of skin disease. The modern stressful lifestyles, lack of adequate physical activities, and associated risk of metabolic syndrome. A lots of research work has already been done in but still a promising cure for Psoriasis is not found.
3. Modern medicine treats Psoriasis with PUVA, Topical and Systemic corticosteroids and anti mitotic drugs which give serious side effects like bone marrow depletion, liver toxicity, and also having recurrence of disease.
4. *Ayurveda* has a great potential in the management of Psoriasis and its associated complications.
5. Since every person is not suitable for *Shodhana chikitsa* , so in present study focusing on *Shaman chikitsa* for *Sidhma Kushtha.*
6. Since *Kushtha* is a *Tridoshaja Vyadhi,* it also a *rakta pradoshaja vikara*, and *Sidhma Kushtha* is a *Vata Kapha* dominant disorder.So *Kushthadalan Ras, Darvyadi Kwath* and *Somraji Taila*may be effective in the *Shaman* of *vata* , *kapha* as well as *rakta dosha* of *Sidhma Kushtha* (Psoriasis Vulgaris ).
**Hypothesis:**
**Null** **Hypothesis Ho:**
There is no difference between the efficacy of *Kushthadalan Ras &* *Somraji Taila* and *Darvyadi Kwath & Somraji Taila* in the management of *Sidhma Kushtha* W.S.R. to Psoriasis Vulgaris.
**Follow up:**After 15 days, 30th day, 45th day, and after completion of trial.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 30
- Patients having chronicity of Psoriasis less then 5 years duration.
- Patient having any clinical signs and symptoms of Sidhma Kushtha as per Ayurvedic classics and Psoriasis as per modern classics.
- 2.1. Sveta tamra varna (white coppary in colour) 2.2. Tanu ( thin) 2.3. Alabupushpavarnam [resembles the flower of alabu (Lagenaria siceraria) discoloration] 2.4. Ghrustam vimunchati (scaling) 2.5. Rukshta (dryness) 2.6. Kandu (itching) 2.7. PASI Score 3.
- Patient willing to give consent for clinical trial.
- Patients on long term steroid and cytotoxic drugs.
- Patients having illness like uncontrolled HTN,DM-II and Cardiac and Renal disorders, malignant diseases, major liver disorders, immunocompromised hosts etc.
- Pregnant and lactating women.
- Patients having complications of psoriasis like psoriasis arthropathy.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes in the PASI SCORE 60 DAYS
- Secondary Outcome Measures
Name Time Method •Changes in Subjective parameters 1.Kandu (Itching index)
Trial Locations
- Locations (1)
National Institute of Ayurveda Hospital Jaipur
🇮🇳Jaipur, RAJASTHAN, India
National Institute of Ayurveda Hospital Jaipur🇮🇳Jaipur, RAJASTHAN, IndiaDr Preeti SahuPrincipal investigator9636922840preetirobinson72@gmail.com