Improving diarrhoea management in children through the development of rotavirus diarrhoea diagnostic kits and viral diarrhoea awareness to reduce diarrhoea illness and death
Not Applicable
Completed
- Conditions
- Rotavirus Group A (RVA) diarrhoeaInfections and Infestations
- Registration Number
- ISRCTN15812702
- Lead Sponsor
- Obafemi Awolowo University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 186
Inclusion Criteria
Cases:
1. Children (aged 0 to 60 months)
2. Acute diarrheal episode (diarrhoea will be defined as three or more loose stools in the last 24 hours with or without other symptoms such as fever, vomiting or dehydration and the onset must be within the last 7 days)
Controls:
1. Healthy children coming to the same hospital/health centre for routine immunization and not presenting with gastroenteritis symptoms for the past 14 days
Exclusion Criteria
Cases:
1. Children who do not have diarrhoea
2. Children older than 5 years
3. Parents or guardians do not give formal consent to participate in the study
Controls:
1. Sick children
2. Children older than 5 years
3. Parents or guardians do not give formal consent to participate in the study
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method RVA detected using ELISA, PCR and the developed nanoparticle-based RVA kit at the end of 1-year sample collection
- Secondary Outcome Measures
Name Time Method Sociodemographic, environmental/clinical/risk factors associated with diarrhoea assessed using a structured questionnaire during the 1-year study period