NCT00886912Unknown不适用
Prevention of Acute Mountain Sickness (AMS) by Intermittent Hypoxic Training
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Incidence of acute mountain sickness
研究概览
简要总结
Some studies suggest that high-altitude related illnesses - like acute mountain sickness - could be prevented by acclimatisation, reached at low altitude using training in simulated altitude. The purpose of this study is to determine whether training in hypoxia is suitable to prevent acute mountain sickness.
详细描述
In a three week-period, healthy probands undergo 3 times a week a bicycle ergometer training in simulated altitude followed by 1 week passive exposure at simulated low altitude. 5 days after last exposure, a field study starts performing a rapid ascent to the Capanna Regina Margherita (4559m). Acute mountain sickness is assessed by established scoring systems.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •non-smoker
- •endurance training min. 2x/week
排除标准
- •any diseases
- •previous exposure to altitudes higher than 2000m (last 6 weeks)
结局指标
主要结局
Incidence of acute mountain sickness
时间窗: after 20 hours at 4559m
次要结局
- Severity of acute mountain sickness(after 20 hours at 4559m)
研究者
研究点 (2)
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