Effect of dexamethasone or ibuprofen-acetaminophen combination for pain management in symptomatic apical periodontitis during COVID-19 outbreak: a retrospective cohort study

Not Applicable

• Conditions: tooth pain; Pain; Endodontic emergency; Ibuprofen; Acetaminophen; COVID 19; Dexamethasone

• Registration Number: TCTR20201027002
• Lead Sponsor: A

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-10-27
• Study Completion: 2020-10-27
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

1) age, 18â€65 years, 2) maxillary\ mandibular molar tooth with symptomatic apical periodontitis and vital pulp, 3) the given medications were the same (ibuprofen 600 mg + acetaminophen 500 mg twice for 3 days or 4 mg dexamethasone twice for 1 day) and 4) complete clinical/radiographic data and pain levels at baseline, 6, 12, 18, 24, 48 and 72 hours.

Exclusion Criteria

1) necrotic pulp, 2) periapical index score 4 and 5 proposed by Ørstavik et al. [12], 3) pregnancy and systemic disease or allergic reactions, 4) sensitivity or adverse reactions to medicines, 5) taken any analgesics or anti-inflammatory drug within the last 3 days, 6) swelling or acute/chronic abscess, 7) active orthodontic appliances and 8) multiple carious teeth.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
pain a week vas

Secondary Outcome Measures

Name	Time	Method
pain on percussion 1 week vas