Physical activity and health: the effect of GoldFit YMCA participation on central and peripheral chemoreflexes and cerebrovascular reactivity in older adult humans

niversity of Auckland0 个研究点目标入组 50 人开始时间: 2022年1月17日最近更新: 2022年1月24日

适应症

试验速览

暂无简介。

•Aged >60 years old
•- Men and women
•- Free of chronic cardiovascular, respiratory, metabolic, or neurological disease
•- Not currently engaging in regular exercise and have not been in a regular exercise routine for >12 months, and who are newly enrolled or intending to enroll to begin exercise training in the YMCA GoldFit exercise training programme, aged >60 years old

•BMI <18 kg/m2
•Current smoker
•Current users of recreational drugs
•Current abusers of alcohol
•Recent (<12 month) history of hospital admission
•Significant arrhythmias (e.g., atrial fibrillation, previous VT / significant ventricular ectopy)
•Hemodynamically significant valvular heart disease (e.g., stenosis, mechanical valve replacement)
•Severe left ventricular systolic dysfunction
•Recent acute coronary syndrome (<12 months) (e.g., MI, angioplasty, unstable angina)
•Previous coronary artery bypass surgery
•Secondary causes of hypertension (e.g., phaeochromocytoma)
•Recent stroke/TIA (<12 months)
•Inability to fully or appropriately provide consent (e.g., language issue, reading capability)
•Underlying medical conditions, which in the opinion of the Investigator place the participant at unacceptably high risk for participating in the study.
•Chronic and systemic illness including:
•Severe respiratory disease (e.g., chronic obstructive pulmonary disease);
•Severe, uncontrolled type II diabetes;
•Current treatment for cancer or complete remission <5 years
•Connective tissue or inflammatory disease
•Neurological / psychiatric disease (e.g., peripheral neuropathy, dementia, Parkinson’s, epilepsy)
•Infection or pyrexial illness
•Uncontrolled thyroid disorders
•Renal impairment (e.g., eGFR <60)
•Liver disease

发起方

niversity of Auckland