Analysis of the Incidence of Expression of Tumor Antigens and Tumor Marker in Cancer Tissue From Asian Patients With Hepatocellular Carcinoma and Evaluation of Prognostic Significance of These Tumor Antigens.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- The prognostic character of the expression of the tumor antigens
研究概览
简要总结
Hepatocellular carcinoma is an aggressive disease with limited therapeutic options. Therefore, new approaches to treat this type of cancer are needed with immunotherapy potentially being one of these. As a first step in the development of novel therapies, expression analysis of specific markers, including tumor antigens will be carried out, and the correlation of expression with disease variables and clinical outcome will be assessed. This will be done retrospectively using archived hepatocellular carcinoma tissue samples.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The patient has pathologically proven hepatocellular carcinoma (any stage)
- •All the data required are available from patient's records
排除标准
- 未提供
结局指标
主要结局
The prognostic character of the expression of the tumor antigens
时间窗: At the time of analysis
Expression of c-MET in the same hepatocellular carcinoma tumor samples
时间窗: At the time of analysis
The proportion of hepatocellular carcinoma patients whose tumor tissue expresses specific tumor antigens.
时间窗: At the time of analysis
次要结局
未报告次要终点