Prehabilitation and Rehabilitation for Patients With Oesophageal Cancer
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 25
- 试验地点
- 1
- 主要终点
- Adherence to exercise sessions.
研究概览
简要总结
Patients with oesophageal cancer selected for oncological and surgical treatment with curative intent are offered supervised physiotherapy and home-based training before and after surgery.
详细描述
Patients with loco-regional oesophageal cancer who will receive neoadjuvant chemotherapy or chemoradiotherapy followed by surgery and sometimes adjuvant chemotherapy are eligible to be enrolled in the trial. Study treatment is supervised group training twice weekly and home-based training three times weekly during neoadjuvant treatment and after surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Histopathologically confirmed squamous cell carcinoma, adenocarcinoma or adenosquamous carcinoma in the oesophagus or cardia (Siewert I or II), cT1 N+ or cT2-4a any N, M0, according to the 8th version of the AJCC TNM classification.
- •Assessed at a multidisciplinary conference to be suitable for curatively intended oncological and surgical treatment.
- •Age > 18 years.
- •Performance status ECOG 0-
- •Patient has provided written informed consent.
排除标准
- •Previous radiotherapy in the thorax (except for tangential field radiotherapy for breast cancer).
- •Inability to understand written and spoken instructions and to comply with protocol requirements.
结局指标
主要结局
Adherence to exercise sessions.
时间窗: Up to 40 weeks
Percentage of sessions completed out of number of sessions planned
Un-planned interruptions in the prehabilitation/rehabilitation programme
时间窗: Up to 40 weeks
Percentage of patients having an unplanned interruption of ten days or more of the supervised prehabilitation/rehabilitation programme
次要结局
未报告次要终点
研究者
Gabriella Alexandersson von Döbeln
Principal Investigator
Karolinska University Hospital