Prehabilitation and Rehabilitation for Patients With Oesophageal Cancer
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Esophageal Cancer
- Sponsor
- Gabriella Alexandersson von Döbeln
- Enrollment
- 25
- Locations
- 1
- Primary Endpoint
- Adherence to exercise sessions.
- Last Updated
- 4 years ago
Overview
Brief Summary
Patients with oesophageal cancer selected for oncological and surgical treatment with curative intent are offered supervised physiotherapy and home-based training before and after surgery.
Detailed Description
Patients with loco-regional oesophageal cancer who will receive neoadjuvant chemotherapy or chemoradiotherapy followed by surgery and sometimes adjuvant chemotherapy are eligible to be enrolled in the trial. Study treatment is supervised group training twice weekly and home-based training three times weekly during neoadjuvant treatment and after surgery.
Investigators
Gabriella Alexandersson von Döbeln
Principal Investigator
Karolinska University Hospital
Eligibility Criteria
Inclusion Criteria
- •Histopathologically confirmed squamous cell carcinoma, adenocarcinoma or adenosquamous carcinoma in the oesophagus or cardia (Siewert I or II), cT1 N+ or cT2-4a any N, M0, according to the 8th version of the AJCC TNM classification.
- •Assessed at a multidisciplinary conference to be suitable for curatively intended oncological and surgical treatment.
- •Age \> 18 years.
- •Performance status ECOG 0-
- •Patient has provided written informed consent.
Exclusion Criteria
- •Previous radiotherapy in the thorax (except for tangential field radiotherapy for breast cancer).
- •Inability to understand written and spoken instructions and to comply with protocol requirements.
Outcomes
Primary Outcomes
Adherence to exercise sessions.
Time Frame: Up to 40 weeks
Percentage of sessions completed out of number of sessions planned
Un-planned interruptions in the prehabilitation/rehabilitation programme
Time Frame: Up to 40 weeks
Percentage of patients having an unplanned interruption of ten days or more of the supervised prehabilitation/rehabilitation programme