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single-dose clinical study evaluating efficacy and safety of standard intramuscular preparation of Paracetamol available in the market for the management of fever

Phase 3
Conditions
Health Condition 1: R509- Fever, unspecified
Registration Number
CTRI/2018/10/016216
Lead Sponsor
Troikaa Pharmaceuticals Limited
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1 Having fever oral temperature between 101 to 104 F both inclusive of

recent onset more than 3 days and expected to be hospitalized more than 24 hrs

2 Willing to comply with study requirements including periodic

measurements or examinations laboratory investigations and avoiding

any intramuscular administration during the entire study

duration of 7 days as documented by provision of written Informed

Consent prior to participation in the study

Exclusion Criteria

1 Fever suspected to be due to neurological infection or any cancer

2 Patient receiving any IM injection for the co morbid condition and where the IM injection are expected to continue

3 High grade fever more than 104 F or suspected septicemia

4 Hypotension inferred from systolic blood pressure more than 90 mmHg

5 Admission in intensive care unit or intensive cardiac care unit

6 Severe kidney creatinine more than 2 mg per dl or liver disease SGOT and SGPT more than 3 times ULN and based on discretion of the investigator

7 Patients with serum CPK levels more than 5 times the ULN for that gender

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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