Effect of Body Mass Index on Intracytoplasmic Sperm Injection Cycles
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 350
- 主要终点
- Clinical Pregnancy Rate After ICSI
研究概览
简要总结
This retrospective cohort study aims to evaluate the effect of body mass index on the outcomes of intracytoplasmic sperm injection (ICSI) cycles at Assiut Women Health Hospital.
详细描述
Obesity is associated with alterations in reproductive function and may affect the success of assisted reproductive techniques. This observational study will review medical records of women who underwent ICSI cycles.
Patients will be classified according to the World Health Organization body mass index categories: underweight (<18.5 kg/m²), normal weight (18.5-24.99 kg/m²), overweight (25-29.99 kg/m²), and obese (≥30 kg/m²). Pregnancy outcomes will be compared across BMI groups.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Women who underwent ICSI cycles at Assiut Women Health Hospital
- •Recorded weight and height at the start of treatment
排除标准
- •Cases with no recorded weight or height at registration
研究组 & 干预措施
Underweight
BMI < 18.5 kg/m² Women classified according to World Health Organization body mass index categories who underwent ICSI cycles.
Normal weight
BMI 18.5-24.99 kg/m² Women classified according to World Health Organization body mass index categories who underwent ICSI cycles.
Overweight
BMI 25-29.99 kg/m² Women classified according to World Health Organization body mass index categories who underwent ICSI cycles.
Obese
BMI ≥ 30 kg/m² Women classified according to World Health Organization body mass index categories who underwent ICSI cycles.
结局指标
主要结局
Clinical Pregnancy Rate After ICSI
时间窗: At 6 weeks after embryo transfer
Proportion of women achieving clinical pregnancy defined as positive serum beta-hCG and presence of gestational sac on ultrasound among total ICSI cycles stratified by BMI groups
次要结局
- Ongoing Pregnancy Rate(At 12 weeks after embryo transfer)
- Clinical Abortion Rate(Up to 20 weeks after embryo transfer)
- Live Birth Rate(At 40 weeks after embryo transfer)
研究者
Hager Mikhamer Mohamed sayed
Resident Physician
Assiut University