EUCTR2008-003696-43-NL
Active, not recruiting
Not Applicable
Prevention of progression of duodenal adenomas to cancer in patients with familial adenomatous polyposis - Duodenal adenomas and cancer in patients with FAP
KWF Kankerbestrijding0 sitesStarted: November 11, 2008Last updated:
Overview
- Phase
- Not Applicable
- Status
- Active, not recruiting
- Sponsor
- KWF Kankerbestrijding
Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional clinical trial of medicinal product
Eligibility Criteria
- Sex
- All
Inclusion Criteria
- •Patients with FAP with duodenal adenomas Spigelman stage II and III, under regular controle in one of 4 participating University hospitals.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1\.2 Adults (18\-64 years) yes
- •F.1\.2\.1 Number of subjects for this age range
- •F.1\.3 Elderly (\>\=65 years) yes
- •F.1\.3\.1 Number of subjects for this age range
Exclusion Criteria
- •\- History of cardiovascular incident
- •\- Cholelithiasis
- •\- History of gastric or duodenal ulcera
- •\- Allergic reaction to NSAIDs or UDCA
- •\- Renal function disturbance, creat clearance \<50ml/min
- •\- Liver function disturbance, albumin \<25g/l or Child\-Pugh\-score \> or \= 10
- •\- Use of NSAIDs or UDCA during enrolment
- •\- Cardiac patients NYHA class II\-IV
- •\- Age below 18 or above 70 years or incapable of signing informed consent
Investigators
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