NCT06431282招募中不适用
In Vivo Visualisation of Hyaluronic Acid After CO2 Laser Compared to Thulium Laser Treatment
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Size of keratinocytes
研究概览
简要总结
- Weakly crossed-linked hyaluronic acid (HA) can be delivered through multiple injections into the dermal and subnormal layer to improve skin quality. However, this treatment comes with multiple bumps for several days.
- Alternatively, HA can be delivered after CO2 laser or thulium laser pretreatment. As microscopic analysis after this treatment is limited, the object of the present study is to investigate the morphological cellular changes after CO2 laser and thulium laser delivered HA into human skin.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •healthy male and female patients
排除标准
- •pregnancy, breast feeding
- •open wounds at the area to be treated
结局指标
主要结局
Size of keratinocytes
时间窗: 30 minutes and 30 days after treatment.
Size of keratinocytes after CO2 or thulium laser treatment compared to control.
Size of hyaluronic acid granules
时间窗: 30 minutes and 30 days after treatment.
Size of HA granules after CO2 or thulium laser treatment compared to control.
Size of intercellular spaces
时间窗: 30 minutes and 30 days after treatment.
Size of intercellular spaces after CO2 or thulium laser treatment compared to control.
Distribution of Hyaluronic Acid
时间窗: 30 minutes and 30 days after treatment.
Distribution though the epidermal and dermal layers after CO2 or thulium laser treatment compared to control.
次要结局
未报告次要终点
研究者
Lynhda Nguyen
Principle Investigator
Universitätsklinikum Hamburg-Eppendorf
研究点 (2)
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