Prevalence and Risk Factors of Erectile Dysfunction in Type 2 Diabetic Patients
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Type 2 Diabetic Patients
- Sponsor
- University of Pavia
- Enrollment
- 220
- Locations
- 1
- Primary Endpoint
- Prevalence of erectile dysfunction
- Status
- Completed
- Last Updated
- 11 years ago
Overview
Brief Summary
The investigators evaluated 250 male, type 2 diabetic patients, aged 18-80 years. They will undergo IIEF (International Index of Erectile Function), SAS of Zung (self-rating anxiety state)and SDS of Zung (self-rating depression scale)questionnaires. The investigators will evaluate anthropometric and biochemical parameters, dysautonomic function index, IMT (Intima Media Thickness) index, and fundus oculi examen. Furthermore, the investigators will perform MNSI (Michigan Neuropathy Screening Instrument) and NDS (Neuropathy Disability Score)questionnaires.
Investigators
Giuseppe Derosa
Professor
University of Pavia
Eligibility Criteria
Inclusion Criteria
- •type 2 diabetes mellitus
Exclusion Criteria
- •type 1 diabetes mellitus
- •\< 18 years old
- •anatomic abnormalities of the penis
- •patients taking erectile dysfunction therapy at the moment of the enrollment
Outcomes
Primary Outcomes
Prevalence of erectile dysfunction
Time Frame: Baseline (time 0); 3 months; 6 months
Evaluation of diabetic neuropathy in patients with erectile dysfunction
Time Frame: Baseline (time 0); 3 months; 6 months
Description of erectile disfunction markers
Time Frame: Baseline (time 0); 3 months; 6 months
Secondary Outcomes
- Metalloproteinases 2 and 9(Baseline (time 0); 3 months; 6 months)
- Insulin-sensitivity index (HOMA index)(Baseline (time 0); 3 months; 6 months)
- Glycemic control(Baseline (time 0); 3 months; 6 months)