Prevalence and Risk Factors of Erectile Dysfunction in Type 2 Diabetic Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 220
- 试验地点
- 1
- 主要终点
- Prevalence of erectile dysfunction
研究概览
简要总结
The investigators evaluated 250 male, type 2 diabetic patients, aged 18-80 years. They will undergo IIEF (International Index of Erectile Function), SAS of Zung (self-rating anxiety state)and SDS of Zung (self-rating depression scale)questionnaires. The investigators will evaluate anthropometric and biochemical parameters, dysautonomic function index, IMT (Intima Media Thickness) index, and fundus oculi examen. Furthermore, the investigators will perform MNSI (Michigan Neuropathy Screening Instrument) and NDS (Neuropathy Disability Score)questionnaires.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •type 2 diabetes mellitus
排除标准
- •type 1 diabetes mellitus
- •< 18 years old
- •anatomic abnormalities of the penis
- •patients taking erectile dysfunction therapy at the moment of the enrollment
结局指标
主要结局
Prevalence of erectile dysfunction
时间窗: Baseline (time 0); 3 months; 6 months
Evaluation of diabetic neuropathy in patients with erectile dysfunction
时间窗: Baseline (time 0); 3 months; 6 months
Description of erectile disfunction markers
时间窗: Baseline (time 0); 3 months; 6 months
次要结局
- Metalloproteinases 2 and 9(Baseline (time 0); 3 months; 6 months)
- Insulin-sensitivity index (HOMA index)(Baseline (time 0); 3 months; 6 months)
- Glycemic control(Baseline (time 0); 3 months; 6 months)
研究者
Giuseppe Derosa
Professor
University of Pavia