Evaluation of a standardized therapy regimen in early rehabilitation for ICU acquired weakness - Early-CIP Study

Not Applicable

• Conditions: G62.8; Other specified polyneuropathies

• Registration Number: DRKS00033177
• Lead Sponsor: Cellitinnen Krankenhaus St. Marien

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-12-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 124

Inclusion Criteria

Women and men who have developed an ICU acquired weakness after intensive care treatment and who have signed the declaration of consent. Inclusion can also take place after the signature of the legal representative in the event that the patient is temporarily unable to give consent.

Exclusion Criteria

- pregnancy
- Leg amputation or other cause of inability to walk even before critical illness (crutches or walkers are no exclusion criteria)
- Previously known severe dementia or other cause of higher-grade cognitive deficits
- Other neuromuscular diseases (GBS, ALS, myasthenia gravis)
- Long-term steroid therapy and Cushing's disease
- Acute stroke
- Acute myocardial infarction
- Acute fractures, unstable cervical spine or pathological Fractures
- Multi-resistant germs that leave the room

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Measurement of physical autonomy using the SINGER scale, surveyed on admission and discharge

Secondary Outcome Measures

Name	Time	Method
- Neurological examination including gait parameters, muscle strength, Delirium, Anxiety and Depression, electrophysiology<br>- Laboratory values<br>- discharge management (death, further rehabilitation, nursing home)<br>- long-term success of intervention (survival, quality of life, workability)