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Effect of VascuActive Device on Foot Perfusion, Hemodynamics and Exercise Capacity in Patients With PVD & Limb Ischemia

Not Applicable
Completed
Conditions
Peripheral Vascular Diseases
Registration Number
NCT01014377
Lead Sponsor
VascuActive LTD
Brief Summary

The purpose of this study is to assess the safety and the immediate effect of the VascuActive device on patients with peripheral vascular disease and limb ischemia.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
15
Inclusion Criteria
  • Leg Ischemia, Fontaine grade IIa and IIb, i.e.: pain free walking distance in the range of 50 - 100 meters.
  • Absent pulses in the two foot arteries (Anterior Tibial a., Posterior Tibial a.)
  • ABI < 0.7 by Doppler, in at least one of the two foot arteries
Exclusion Criteria
  • Absent femoral pulses
  • Venous insufficiency by Duplex
  • Pregnancy
  • Infectious disease
  • Malignant disease
  • Severe cardiac disease, e.g., CHF grade 3 or higher
  • Acute MI within last 3 months
  • CABG within last 3 months
  • Other severe systemic disease

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
Pain-free and Maximal walking distance1 hour
Secondary Outcome Measures
NameTimeMethod
Transcutaneous partial pressure of O2 and CO21 hour
Skin temperature1 hour
Skin blood flow1 hour

Trial Locations

Locations (1)

Asaf Harofe Medical Center

🇮🇱

Zrifin, Israel

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