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Clinical Trials/NCT04780178
NCT04780178
Completed
Not Applicable

Telephone Acceptance and Commitment Therapy Intervention for Caregivers of Adults With Alzheimer's Disease and Related Dementias (TACTICs): A Pilot Randomized Controlled Trial (RRF)

Indiana University1 site in 1 country60 target enrollmentApril 1, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Anxiety
Sponsor
Indiana University
Enrollment
60
Locations
1
Primary Endpoint
Generalized Anxiety Disorder Scale (GAD-7)
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

The purpose of the study is to test if Acceptance and Commitment Therapy (ACT), a behavioral intervention designed to increase psychological flexibility in the face of challenges, reduces anxiety associated psychological distress in dementia caregivers compared to the control group who will receive self-help and educational materials. This version of ACT is delivered over the phone in six primary sessions and one booster session.

Registry
clinicaltrials.gov
Start Date
April 1, 2021
End Date
August 8, 2022
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Nicole R. Fowler, PhD

Associate Professor of Medicine

Indiana University

Eligibility Criteria

Inclusion Criteria

  • Listed in ADRD patient's chart as primary caregiver or self-identifies as ADRD patient's primary caregiver
  • Intends to continue caregiving for ≥12 months
  • Clinically-significant anxiety (score ≥10 on GAD-7)
  • 21 years or older
  • Able to communicate in English
  • Able to provide informed consent

Exclusion Criteria

  • Caregiver is a non-family member
  • Care recipient is in an assisted living or nursing home (at baseline)
  • Has ADRD or other serious mental illness diagnosis such as schizophrenia as determined by ICD-10 code or self-report
  • Caregiver is enrolled in an existing ADRD collaborative program at Eskenazi Health, IU Health or the VA.
  • Caregiver is enrolled in another IU study that is testing a ADRD caregiver intervention

Outcomes

Primary Outcomes

Generalized Anxiety Disorder Scale (GAD-7)

Time Frame: Baseline, post-intervention (7-9 weeks post-baseline), 3-month, 6-month

The Generalized Anxiety Disorder Scale (GAD-7) contains 7 items with total scores ranging from 0 to 21. Scores of 5, 10, and 15 are cut-offs for mild, moderate, and severe anxiety, respectively. An add-on item assessing the patient's global impression of symptom-related impairment helps researchers understand the extent to which anxiety interferes in daily life. The GAD-7 has factorial validity for the diagnosis of general anxiety disorder and is sensitive to change.

Study Sites (1)

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