DRKS00032459
招募中
不适用
Establishment of a biomaterial bank to study biomarkers in the context of neurodegenerative diseases.
Klinik für Psychiatrie und Psychotherapie, Universitätsmedizin Göttingen0 个研究点目标入组 2,000 人2023年9月11日
概览
- 阶段
- 不适用
- 干预措施
- 未指定
- 疾病 / 适应症
- eurodegenerative diseases as well as healthy controls and controls with other psychiatric diseases.
- 发起方
- Klinik für Psychiatrie und Psychotherapie, Universitätsmedizin Göttingen
- 入组人数
- 2000
- 状态
- 招募中
- 最后更新
- 去年
概览
简要总结
暂无简介。
研究者
入排标准
入选标准
- •Participation as a biomaterial donor in this study is possible if the following inclusion criteria are met:
- •(a) a neurodegenerative disease or cognitive impairment is suspected or has been diagnosed,
- •(b) there is central nervous disease or a suspicion of such disease without clinical evidence of a neurodegenerative component or cognitive impairment, if the indication for lumbar puncture is present.
- •(c) In addition, control subjects may be allowed to participate in the study provided there is no suspicion of CNS disease.
- •Subjects may be included only under the following conditions:
- •(d) the respective subject (or a representative according to a legal authorization) agrees with biomaterial collections in terms of donation and storage as well as the subsequent analyses and is capable of this expression of intent
- •(e) the subjects agree after sufficient information about the scientific background as well as the aims of the study and confirm this in writing in the consent form.
排除标准
- •Exclusion criteria for subjects are the following:
- •(a) they do not consent to the blood and CSF donations and subsequent analyses.
- •(b) There is a lack of capacity to consent of the proband without a legal representative (health care proxy or legal guardian) being available (blood and CSF donations).
- •(c) there is accommodation in accordance with the Lower Saxony Law on Assistance and Protective Measures for the Mentally Ill (NPsychKG).
- •(d) there is a known infectious disease. If an infectious disease is subsequently diagnosed, the corresponding samples are to be destroyed in accordance with the hygiene guidelines.
- •(e) reliable data for diagnosis are not available and cannot be collected at reasonable cost to subjects and investigators.
- •(f) there is oral anticoagulation (Marcumar or new oral anticoagulants) , which would lead to refraining from lumbar puncture or skin biopsy in the context of routine clinical diagnostics. Nevertheless, blood donation is possible in such a case.
- •On the other hand, skin biopsy will only be performed in patients capable of giving consent.
结局指标
主要结局
未指定
相似试验
尚未招募
不适用
Deployment of a biobank for research and identification of biomarkers predicting postoperative Crohn*s disease recurrence: RAP-CD ancillary studyNL-OMON47935Erasmus MC, Universitair Medisch Centrum Rotterdam50
已完成
不适用
Establishment of a biobank for molecular biological investigations in benign and malignant diseases of the thorax and gastrointestinal tract associated with cachexiaR64M62.5CachexiaMuscle wasting and atrophy, not elsewhere classifiedDRKS00017285Klinik und Poliklinik für Chirurgie Klinikum rechts der Isar Technische Universität München119
招募中
不适用
A tissue bank for biomarker research on fresh frozen tumor samplescancer10027656NL-OMON40050Jeroen Bosch Ziekenhuis400
招募中
不适用
Biobanking for characterization of pediatric malignancies.NL-OMON21619Prinses Maxima Centrum voor kinderoncologie2,750
招募中
不适用
Development of a database and biobank facility for the collection of clinical data and the storage of biological samples, such as tissue, blood and urine, in patients with bladder and urothelial cancer (BLADDA).ACTRN12618000914268Walter and Eliza Hall Institute for Medical Research300