NCT06245720Active, not recruitingNot Applicable
Serum and Urine Metabolome Studies in Patients With Acute Kidney Injury After Cardiac Surgery
Nanjing First Hospital, Nanjing Medical University1 site in 1 country200 target enrollmentStarted: January 1, 2024Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Active, not recruiting
- Enrollment
- 200
- Locations
- 1
- Primary Endpoint
- serum and urine metabolome studies
Study Overview
Brief Summary
The goal of this observational study is to learn about serum and urine metabolome in patients after cardiac surgery.
Detailed Description
The main objective of this study is to collect blood and urine samples from patients after cardiac surgery, and to perform metabolomic analysis to find the differential metabolites and their enrichment pathways in AKI patients and non-AKI patients.The secondary objective is to intervene in its enrichment pathway to find ways to improve CSA-AKI.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Cross Sectional
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Age> 18 years old;
- •after cardiopulmonary bypass;
Exclusion Criteria
- •Under the age of 18;
- •Previous chronic kidney disease or receiving renal replacement therapy;
- •Have a history of kidney transplantation or nephrectomy.
Outcomes
Primary Outcomes
serum and urine metabolome studies
Time Frame: January 2025 - December 2025
The preoperative and postoperative metabolomic differences in blood and urine between AKI group and non-AKI group were compared.
Secondary Outcomes
No secondary outcomes reported
Investigators
Study Sites (1)
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