NCT06245720
Active, not recruiting
Not Applicable
Serum and Urine Metabolome Studies in Patients With Acute Kidney Injury After Cardiac Surgery
Nanjing First Hospital, Nanjing Medical University1 site in 1 country200 target enrollmentJanuary 1, 2024
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Cardiac Surgery Associated Acute Kidney Injury
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
- Enrollment
- 200
- Locations
- 1
- Primary Endpoint
- serum and urine metabolome studies
- Status
- Active, not recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
The goal of this observational study is to learn about serum and urine metabolome in patients after cardiac surgery.
Detailed Description
The main objective of this study is to collect blood and urine samples from patients after cardiac surgery, and to perform metabolomic analysis to find the differential metabolites and their enrichment pathways in AKI patients and non-AKI patients.The secondary objective is to intervene in its enrichment pathway to find ways to improve CSA-AKI.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age\> 18 years old;
- •after cardiopulmonary bypass;
Exclusion Criteria
- •Under the age of 18;
- •Previous chronic kidney disease or receiving renal replacement therapy;
- •Have a history of kidney transplantation or nephrectomy.
Outcomes
Primary Outcomes
serum and urine metabolome studies
Time Frame: January 2025 - December 2025
The preoperative and postoperative metabolomic differences in blood and urine between AKI group and non-AKI group were compared.
Study Sites (1)
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