Serum exosomal miRNA/LncRNA as potential biomarkers for Early detection and monitoring progression of gastric cancer and observation on therapeutic effect of Traditional Chinese Medicine on gastric precancerous lesions
- Conditions
- Gastric cancer and precancerous lesions
- Registration Number
- ITMCTR2000003958
- Lead Sponsor
- Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
120 cases came from outpatients and inpatients in the Department of Gastroenterology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine. Diagnosis refers to the relevant standards in the Chinese Consensus on Chronic Gastritis (Chinese Medical Association Gastroenterology Branch. China Chronic Gastritis Consensus (2017, Shanghai). Gastroenterology, 2017, 22(11):670-687).
1. All participants must meet the above diagnostic criteria, that is, chronic atrophic gastritis, especially patients with moderate to severe intestinal metaplasia or dysplasia (intraepithelial neoplasia);
2. Aged 20 to 75 years old;
3. signed informed consent.
1. Patients confirmed by pathological examination to have cancer;
2. Patients with major organ diseases, it is difficult to complete the clinical trial program;
3. Patients with mood disorders and cognitive disorders;
4. Patients during pregnancy and lactation.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum exosomal miRNA/LncRNA;Pathology;Electronic gastroscope;Pepsinogen;
- Secondary Outcome Measures
Name Time Method