A study of the incidence of molecular mutations in newly diagnosed acute lymphoblastic leukemia (ALL) patients by Next-generation sequencing technique
Recruiting
- Conditions
- Thai newly diagnosed ALL patients aged greater than 18 years.Acute lymphoblastic leukemia, Next-generation sequencing ,Molecular mutations
- Registration Number
- TCTR20240409003
- Lead Sponsor
- Siriraj Hospital Mahidol University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 140
Inclusion Criteria
1.A retrospective cohort: Thai newly diagnosed ALL patients
2.A prospective cohort: Thai newly diagnosed ALL patients aged greater than 18 years who had genetic workup results by NGS study and signed informed consent OR
Exclusion Criteria
Poor quality specimen from a protocol number 388/2561(EC2)
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method incidence of molecular mutations in Thai adult newly diagnosed ALL patients by NGS technique 1 years Next-generation sequencing (targeted gene sequencing: Illumina machine)
- Secondary Outcome Measures
Name Time Method To evaluate the clinical outcome in Thai adult ALL patients considering molecular mutations 1 years Case record form comparing with genetic results by Illumina machine