Efficacy of Hemostasis by Soft Coagulation Using Endoscopic Hemostatic Forceps in Comparison With Argon Plasma Coagulation for Acute Peptic Ulcer Bleeding
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 151
- 试验地点
- 1
- 主要终点
- Recurrence of bleeding within four weeks after initial hemostasis
研究概览
简要总结
Endoscopic high-frequency soft coagulation is available for the management of bleeding or nonbleeding visible vessels during endoscopic submucosal dissection. However, its efficacy on peptic ulcer bleeding has not been elucidated so far. The aim of this study was to evaluate the efficacy of hemostasis with soft coagulation using hemostatic forceps by comparing it with argon plasma coagulation (APC) in a prospective, randomized trial.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age greater than 18 years
- •peptic ulcer with stigmata of recent hemorrhage
排除标准
- •malignant ulcer
- •previous gastric surgery
研究组 & 干预措施
APC group
epinephrine injection plus argon plasma coagulation
干预措施: epinephrine injection plus argon plasma coagulation (Device)
Forceps group
epinephrine injection plus soft coagulation using hemostatic forceps
干预措施: epinephrine injection plus soft coagulation using hemostatic forceps (Device)
结局指标
主要结局
Recurrence of bleeding within four weeks after initial hemostasis
时间窗: up to 24 months
次要结局
- initial hemostasis rate(up to 24 months)
研究者
Jung-Wook Kim
Clinical fellow
Kyunghee University Medical Center