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临床试验/NCT05311202
NCT05311202Unknown不适用

The Effect of Training Volume and Intensity of Acute Resistance Exercise on Inhibitory Control: An Event-Related Potential Study

National Taiwan Normal University2 个研究点 分布在 1 个国家目标入组 175 人开始时间: 2022年4月1日最近更新:
适应症

试验速览

阶段
不适用
入组人数
175
试验地点
2
主要终点
Changes In Neuroelectrical Activities: Event-Related Potential Recording and Analysis

研究概览

简要总结

The current study is a five-arm, single bout program aiming to assess the effects of training volume and intensity of acute resistance exercise on inhibitory control on neurocognitive function with respect to event-related potential in adults aged 20 - 26 years.

详细描述

The current study is expected that 175 healthy adults will be recruited and randomly assigned to control group, low volume-moderate intensity, moderate volume-moderate intensity, high volume-moderate intensity, or moderate volume-low intensity group, with 35 participants in each group. Participants will be required to conduct two experiments. The first was the familiarity experiment, which consisted of the experiment description, the familiarity test, and the 6 Repetition Maximum (RM) test. The process lasted about 3 hours. The exercise group was given a warm-up exercise before the intervention, followed by resistance exercise, including Bench Press, Rowing, Deadlift, and Squat, all completed on the Smith machine. After the exercise, the group was given a cool down, while the control group was given 30 minutes of reading. Before and after the intervention, Stroop, event-related potential and fingertip blood lactate were measured, and another fingertip blood lactate was measured 10 minutes after the intervention, which lasted about 3 hours.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Health Services Research
盲法
None

入排标准

年龄范围
20 Years 至 26 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • The dominant hand is right-handed
  • 18.5 < BMI < 26
  • Can cooperate with fingertip blood collection
  • No color blindness and epilepsy
  • Not taking medications that affect brain function
  • Irregular exercise (more than 150 minutes per week for 3 months)

排除标准

  • The participants who do not meet the inclusion or The Physical Activity Readiness Questionnaire for Everyone (PAR-Q+) Criteria.

结局指标

主要结局

Changes In Neuroelectrical Activities: Event-Related Potential Recording and Analysis

时间窗: 30 minutes each before & after intervention

The continuous electroencephalogram (EEG) activity of each participant will be recorded throughout the entire Stroop task using a Neuroscan Quick-Cap, with 32 Ag/AgCl electrodes arranged following the international 10-20 system (NeuroScan Inc., El Paso, TX, USA). Changes in the neuroelectrical activities before and after the intervention will be examined. The time windows for each ERP component will be determined based on a visual inspection of the averaged grand waveform.

Changes In Inhibitory Control

时间窗: 30 minutes each before & after intervention

The computerized Stroop test will be administrated to assess participants' inhibitory function, and the changes in Emotional Stroop test performance (i.e., response time and accuracy) before (pre-test) and after (post-test) intervention will be examined.

次要结局

  • Muscular Fitness Measurements (1RM)-Bench Press(2 hours on the first day)
  • Muscular Fitness Measurements (1RM)-Squat(2 hours on the first day)
  • Changes In Positive & Negative Affect(5 minutes after pre-test and post-test of Stroop test)
  • Muscular Fitness Measurements (1RM)-Rowing(2 hours on the first day)
  • Muscular Fitness Measurements (1RM)-Deadlift(2 hours on the first day)
  • Changes In Concentration Of Blood Lactate(2 minutes of each time point (Before the pre-test of cognitive test, after the intervention and before the post-test of cognitive test))

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Yu-Kai Chang

Research Chair professor

National Taiwan Normal University

研究点 (2)

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