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Clinical Trials/NCT05311202
NCT05311202UnknownNot Applicable

The Effect of Training Volume and Intensity of Acute Resistance Exercise on Inhibitory Control: An Event-Related Potential Study

National Taiwan Normal University2 sites in 1 country175 target enrollmentStarted: April 1, 2022Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Enrollment
175
Locations
2
Primary Endpoint
Changes In Neuroelectrical Activities: Event-Related Potential Recording and Analysis

Study Overview

Brief Summary

The current study is a five-arm, single bout program aiming to assess the effects of training volume and intensity of acute resistance exercise on inhibitory control on neurocognitive function with respect to event-related potential in adults aged 20 - 26 years.

Detailed Description

The current study is expected that 175 healthy adults will be recruited and randomly assigned to control group, low volume-moderate intensity, moderate volume-moderate intensity, high volume-moderate intensity, or moderate volume-low intensity group, with 35 participants in each group. Participants will be required to conduct two experiments. The first was the familiarity experiment, which consisted of the experiment description, the familiarity test, and the 6 Repetition Maximum (RM) test. The process lasted about 3 hours. The exercise group was given a warm-up exercise before the intervention, followed by resistance exercise, including Bench Press, Rowing, Deadlift, and Squat, all completed on the Smith machine. After the exercise, the group was given a cool down, while the control group was given 30 minutes of reading. Before and after the intervention, Stroop, event-related potential and fingertip blood lactate were measured, and another fingertip blood lactate was measured 10 minutes after the intervention, which lasted about 3 hours.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Health Services Research
Masking
None

Eligibility Criteria

Ages
20 Years to 26 Years (Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • The dominant hand is right-handed
  • 18.5 < BMI < 26
  • Can cooperate with fingertip blood collection
  • No color blindness and epilepsy
  • Not taking medications that affect brain function
  • Irregular exercise (more than 150 minutes per week for 3 months)

Exclusion Criteria

  • The participants who do not meet the inclusion or The Physical Activity Readiness Questionnaire for Everyone (PAR-Q+) Criteria.

Outcomes

Primary Outcomes

Changes In Neuroelectrical Activities: Event-Related Potential Recording and Analysis

Time Frame: 30 minutes each before & after intervention

The continuous electroencephalogram (EEG) activity of each participant will be recorded throughout the entire Stroop task using a Neuroscan Quick-Cap, with 32 Ag/AgCl electrodes arranged following the international 10-20 system (NeuroScan Inc., El Paso, TX, USA). Changes in the neuroelectrical activities before and after the intervention will be examined. The time windows for each ERP component will be determined based on a visual inspection of the averaged grand waveform.

Changes In Inhibitory Control

Time Frame: 30 minutes each before & after intervention

The computerized Stroop test will be administrated to assess participants' inhibitory function, and the changes in Emotional Stroop test performance (i.e., response time and accuracy) before (pre-test) and after (post-test) intervention will be examined.

Secondary Outcomes

  • Muscular Fitness Measurements (1RM)-Bench Press(2 hours on the first day)
  • Muscular Fitness Measurements (1RM)-Squat(2 hours on the first day)
  • Changes In Positive & Negative Affect(5 minutes after pre-test and post-test of Stroop test)
  • Muscular Fitness Measurements (1RM)-Rowing(2 hours on the first day)
  • Muscular Fitness Measurements (1RM)-Deadlift(2 hours on the first day)
  • Changes In Concentration Of Blood Lactate(2 minutes of each time point (Before the pre-test of cognitive test, after the intervention and before the post-test of cognitive test))

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Yu-Kai Chang

Research Chair professor

National Taiwan Normal University

Study Sites (2)

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