Effect of hydroxychloroquine on blood sugars among patients diagnosed with rheumatoid arthritis and diabetes
Phase 4
- Conditions
- Health Condition 1: M959- Acquired deformity of musculoskeletal system, unspecifiedHealth Condition 2: E119- Type 2 diabetes mellitus without complications
- Registration Number
- CTRI/2018/12/016680
- Lead Sponsor
- Dr Asha B
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
2)Rheumatoid arthritis diagnosed based on American College of Rheumatology criteria (both seropositive and seronegative are included)
3)Type II diabetes with any one of the oral drug for diabetes
4)Fasting blood sugar 126-250 mg/dl and Post prandial blood sugar 200- 350mg/dl
5)HbA1c levels in the range of 6.6- 12%
Exclusion Criteria
1)History of taking chloroquine and its derivatives, insulin preparations and corticosteroids or other hormone derivatives in the past 3 months
2)History of allergy to hydroxychloroquine
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1)To determine the effect of hydroxychloroquine on Fasting Blood Sugar (FBS), Post Prandial Blood Sugar (PPBS) and Glycated Hemoglobin (HbA1C) in patients with rheumatoid arthritis and type II diabetes mellitusTimepoint: 3 and 6 months
- Secondary Outcome Measures
Name Time Method 2)To assess the adverse effects in hydroxychloroquine based and non hydroxychloroquine based regimen in the above mentioned patients.Timepoint: 3 and 6 months