NCT04572399已完成不适用
Respiratory Application of a Novel Ultraviolet Light Delivery Device for Patients Infected With COVID-19: A Pilot Study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 5
- 试验地点
- 2
- 主要终点
- Negative Change in Viral Load
研究概览
简要总结
This pilot study will assess the safety and effectiveness of UV light treatment in hospitalized patients with COVID-19.
详细描述
This is a single center, open label, pilot study. 5 adult patients, aged over 18, who are confirmed positive with SARS-CoV-2 and are newly intubed, will receive UV light treatment to reduce SARS-CoV-2 viral load.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Confirmed positive test result for SARS-CoV-2
- •Mechanically ventilated
- •Endotracheal tube inner diameter of at least 7.5 mm
排除标准
- •Unable to provide informed consent (or surrogate)
- •Enrolled in a therapeutic clinical trial for same condition that does not allow recruitment in other trials
- •Pregnant women
结局指标
主要结局
Negative Change in Viral Load
时间窗: 5 days
Change of viral load in upper airway in patients admitted to hospital for COVID-19
次要结局
- Change in Bacterial Load(5 days)
- Ventilated Associated Pneumonia(1 month)
- Catheter Tip Assessment on the Last Day of Treatment(5 days)
- Days to Extubation(1 month)
- Days to Discharge(1 month)
- Change in C-reactive Protein(5 days)
- Change in the World Health Organization (WHO) Coronavirus Disease (COVID)-19 10-point Ordinal Severity Scale by 30 Days(1 month)
研究者
George Chaux
Medical Director, Lung Transplant Program
Cedars-Sinai Medical Center
研究点 (2)
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