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Clinical Trials/NCT07469345
NCT07469345
Enrolling By Invitation
Not Applicable

Bruxism and Pelvic Pain, Erectile Dysfunction, and Anxiety in Young Men: A Cross-Sectional Study

Akdeniz University1 site in 1 country100 target enrollmentStarted: April 16, 2026Last updated:

Overview

Phase
Not Applicable
Status
Enrolling By Invitation
Enrollment
100
Locations
1
Primary Endpoint
Bruxism Assessment

Overview

Brief Summary

Bruxism is a parafunctional activity characterized by clenching or grinding of the teeth during wakefulness or sleep. Increasing evidence suggests that bruxism is not only related to orofacial structures but may also be associated with broader musculoskeletal and psychosocial conditions. Emerging literature indicates that central sensitization, stress, and anxiety may contribute to both bruxism and chronic pain conditions. However, the potential relationship between bruxism and pelvic health outcomes has not been sufficiently investigated.

Pelvic pain and sexual dysfunction, including erectile dysfunction, are multifactorial conditions that may involve neuromuscular, psychological, and autonomic mechanisms. Considering the shared mechanisms related to muscle hyperactivity, stress responses, and central pain modulation, bruxism may be associated with pelvic pain symptoms and sexual dysfunction in men. Additionally, anxiety is recognized as a common contributing factor in both bruxism and pelvic floor dysfunction.

The aim of this cross-sectional study is to investigate the association between bruxism, pelvic pain, erectile dysfunction, and anxiety levels in young adult men. Participants will be assessed using validated self-report questionnaires to evaluate bruxism symptoms, pelvic pain complaints, erectile function, and anxiety levels. Understanding the potential relationship between these variables may contribute to a more comprehensive biopsychosocial understanding of male pelvic health and may help guide future multidisciplinary assessment and management strategies.

Detailed Description

Bruxism has been linked with stress, anxiety, autonomic nervous system dysregulation, and central sensitization processes. These mechanisms may also play a role in the development and maintenance of chronic pain conditions beyond the orofacial region.

Pelvic pain and sexual dysfunction in men, including erectile dysfunction, are complex conditions with multifactorial etiologies involving musculoskeletal, neurological, vascular, and psychosocial factors. Increasing evidence suggests that pelvic floor muscle overactivity, stress-related autonomic responses, and psychological distress may contribute to pelvic pain syndromes and sexual dysfunction. Anxiety, in particular, has been identified as an important factor influencing both pelvic floor muscle tension and erectile function.

Given that bruxism is associated with muscle hyperactivity, stress responses, and psychological factors, it is plausible that individuals with bruxism may also experience symptoms related to pelvic floor dysfunction. However, the potential relationship between bruxism and male pelvic health outcomes, such as pelvic pain and erectile dysfunction, has not been sufficiently investigated in the literature. Understanding whether bruxism is associated with pelvic symptoms may provide insight into shared neuromuscular or biopsychosocial mechanisms.

The primary aim of this cross-sectional study is to investigate the association between bruxism and pelvic pain in young adult men. Secondary aims include examining the relationship between bruxism and erectile dysfunction as well as anxiety levels. Participants will be young adult men recruited from the general population. Bruxism status will be assessed using validated self-report measures consistent with current international consensus definitions of probable bruxism. Pelvic pain symptoms, erectile function, and anxiety levels will be evaluated using validated questionnaires.

Statistical analyses will be conducted to examine the relationships between bruxism and pelvic pain, erectile dysfunction, and anxiety. Correlation and group comparison analyses will be used to explore potential associations between these variables. The findings of this study may contribute to a broader understanding of the relationship between orofacial parafunctional activities and pelvic health outcomes. Identifying potential links between bruxism and pelvic floor-related symptoms may help support a multidisciplinary perspective in the assessment and management of men presenting with pelvic pain or sexual dysfunction.

Study Design

Study Type
Observational
Observational Model
Case Control
Time Perspective
Cross Sectional

Eligibility Criteria

Ages
18 Years to 30 Years (Adult)
Sex
Male
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Male participants aged 18-30 years
  • Ability to understand and complete the questionnaires
  • Voluntary participation and provision of informed consent
  • For the bruxism group: self-reported symptoms of teeth clenching or grinding during sleep or wakefulness within the past 6 months

Exclusion Criteria

  • History of neurological disorders affecting motor function
  • Diagnosed psychiatric disorders requiring active treatment
  • Current use of medications that may affect sexual function
  • History of pelvic surgery
  • Known urological diseases affecting erectile function
  • Chronic systemic diseases that may influence pain perception

Arms & Interventions

Bruxism Group

Men who diagnosed bruksizm

Intervention: Questionnaire and Physical Exam (Diagnostic Test)

Non-bruksizm Group

Control group

Intervention: Questionnaire and Physical Exam (Diagnostic Test)

Outcomes

Primary Outcomes

Bruxism Assessment

Time Frame: 6 months

Bruxism will be assessed using self-report questions addressing both awake bruxism and sleep bruxism behaviors. Participants will report the presence and frequency of teeth clenching or grinding during wakefulness or sleep within the past six months. Pain related to bruxism will be evaluated using a Visual Analog Scale (VAS) ranging from 0 to 10, where: 0 represents no pain 10 represents the worst imaginable pain Higher scores indicate greater pain intensity associated with bruxism.

Jaw Function Assessment

Time Frame: 6 months

Jaw functional limitations will be assessed using the Jaw Functional Limitation Scale-20 (JFLS-20). This instrument evaluates functional limitations in three domains: Mastication Jaw mobility Verbal and emotional expression Each item is scored on a 0-10 numeric rating scale, where: 0 indicates no limitation 10 indicates severe limitation The total score is calculated as the mean of the items within each domain or across all items. Higher scores indicate greater functional limitation.

Chronic Prostatitis / Chronic Pelvic Pain Symptoms

Time Frame: 6 months

Pelvic pain symptoms will be assessed using the National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI). The NIH-CPSI includes 9 items across three domains: Pain (0-21) Urinary symptoms (0-10) Quality of life impact (0-12) The total score ranges from 0 to 43, with higher scores indicating more severe symptoms related to chronic prostatitis or chronic pelvic pain syndrome. The validated Turkish version of the NIH-CPSI will be used (Coşkun et al., 2021).

Secondary Outcomes

  • Impact of Pelvic Pain on Daily Life(6 months)
  • Sexual Function Assessment(6 months)
  • Anxiety Assessment(6 months)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Alime Buyuk

PhD,Akdeniz University, Physiotherapy and Rehabilitation Department

Akdeniz University

Study Sites (1)

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