The effect of intermittent sampling on aldosterone lateralisation during adrenal venous sampling (AVS) in patients with primary aldosteronism (PA)

• Conditions: Primary aldosteronism; 10001353

• Registration Number: NL-OMON30899
• Lead Sponsor: niversitair Medisch Centrum Sint Radboud

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

Patients with PA, in whom AVS is indicated

Exclusion Criteria

Patients with increased risk of trombosis

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The variation in lateralisation ratios (i.e. the concentration of aldosterone<br /><br>and cortisol in one adrenal vein compared to the concentrations in the other<br /><br>adrenal vein) at three different moments (t=0, t=15, t=30). </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Evaluation whether determination of cortisol concentration during the procedure<br /><br>is advantageous.</p><br>