NL-OMON21445
Recruiting
N/A
Profiling Parkinson’s disease
Amsterdam UMC, location VUmc0 sites1,515 target enrollmentTBD
ConditionsParkinson's disease
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Parkinson's disease
- Sponsor
- Amsterdam UMC, location VUmc
- Enrollment
- 1515
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •In order to be eligible to participate in this study, a patient must meet ALL of the following criteria:
- •\- Recently diagnosed with PD (N\=625; time since Parkinson diagnosis \= 2 years) or not recently diagnosed with PD (N\=625; time since Parkinson diagnosis \> 2 \& \= 10 years) (Time since Parkinson diagnosis (in years) made by a neurologist according to the Movement Disorder Society clinical diagnostic criteria for Parkinson's disease; In order to obtain a good representation of the PD population an even distribution with respect to gender and age (age categories: \<55 years, 55\-65 years and \>65 years) in both patient groups, will be attempted;
- •\- 18 years or older;
- •\- Able to read and understand Dutch;
- •\- Providing IRB\-approved Informed Consent;
- •\- Willing, competent and able to comply with all aspects of the protocol, including follow\-up schedule and biospecimen collections.
- •\- 18 years or older;
- •\- Healthy (self\-report);
- •\- Similar distribution with respect to gender and age as the patient groups will be attempted;
- •\- Providing IRB\-approved Informed Consent;
Exclusion Criteria
- •A potential participant who meets ANY of the following criteria will be excluded from participation in this study:
- •\- Patients who received brain surgery for Parkinson’s disease, patients who currently use levodopa continuous intestinal gel or patients who are currently receiving apomorphine treatment.
- •\- Presence of co\-morbidities that would hamper interpretation of parkinsonian disability, in the opinion of the investigator;
- •\- MoCa score of \=16 (indicates dementia);
- •\- Unwillingness to be informed of unexpected medical findings;
- •\- Note: patients with a disease duration of \= 2 yrs, are excluded if:
- •\- they are current, recent or past participant in The Personalized Parkinson Project (de Parkinson op maat studie”) from Radboudumc.
- •\- Patients with a disease duration of \> 2 \& \= 10 yrs, are only excluded if they are currently a participant in The Personalized Parkinson Project (de Parkinson op maat studie”) from Radboudumc.
- •\- A history of neurological disorders that affect the brain or central nervous system;
- •\- Abnormal findings at general neurological examination;
Outcomes
Primary Outcomes
Not specified
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