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临床试验/NCT07424768
NCT07424768已完成不适用

Re-operative Hypospadias Repair Using Tubularized Incised Plate Urethroplasty

Tanta University1 个研究点 分布在 1 个国家目标入组 15 人开始时间: 2021年1月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
15
试验地点
1
主要终点
Success rate

研究概览

简要总结

The aim of this study is to evaluate the outcomes, feasibility, and complication profile of re-operative hypospadias repair using tubularized incised plate urethroplasty as a single-stage procedure in a single-center experience.

详细描述

Hypospadias repair remains one of the most common reconstructive procedures in pediatric urology; however, re-operative hypospadias represents a challenging subset due to distorted anatomy, urethral plate scarring, deficient local tissues, and higher complication rates compared with primary repairs.

The tubularized incised plate (TIP) urethroplasty, originally described by Snodgrass, revolutionized primary hypospadias repair and has since been adapted for selected reoperative cases. Contemporary evidence suggests that despite prior surgery and scary, a well-vascularized urethral plate of adequate width can still be successfully tubularized following a midline relaxing incision, offering acceptable functional and cosmetic outcomes.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Retrospective

入排标准

年龄范围
1 Year 至 16 Years(Child)
性别
All
接受健康志愿者

入选标准

  • Both sexes.
  • Children with recurrent or residual hypospadias in whom the urethral plate is deemed suitable for reuse, defined as a plate width of at least 8-9 mm with acceptable vascularity and without severe fibrosis.

排除标准

  • Patients with severely scared or fibrotic urethral plates are not suitable for tubularization.
  • Absent or destroyed urethral plates following previous failed hypospadias repairs.
  • Patients require staged urethral reconstruction rather than a single-stage procedure.
  • Presence of poor urethral plate vascularity or ischemic tissue.
  • Extensive penile scarring or fibrosis resulting from multiple previous surgical attempts.
  • Severe penile curvature requiring excision of the urethral plate.
  • Inability to achieve adequate, well-vascularized tissue coverage over the neourethra.

研究组 & 干预措施

Study group

Children with recurrent or residual hypospadias in whom the urethral plate is deemed suitable for reuse.

干预措施: Tubularized Incised Plate Urethroplasty (Procedure)

结局指标

主要结局

Success rate

时间窗: 6 months after the procedure

The success rate of tubularized incised plate urethroplasty reoperation after treatment was recorded.

次要结局

  • Incidence of complications(6 months after the procedure)
  • Incidence of postoperative urethrocutaneous fistula(6 months after the procedure)
  • Incidence of meatal stenosis(6 months after the procedure)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Rami Mohamed Salama

Lecturer of Pediatric Surgery, Tanta University, Tanta, Egypt.

Tanta University

研究点 (1)

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