ACTRN12623000976684尚未招募4 期
The feasibility of ceftolozane/tazobactam Continuous Infusion for Exacerbations of Cystic Fibrosis and Bronchiectasis Treated in an outpatient parenteral antibiotic therapy (OPAT) Setting
适应症
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomised trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •Age > 18 years
- •Diagnosis of CF or bronchiectasis
- •Colonised with pseudomonas aeruginosa or burkholderia cepacia species, with documented isolation of either organism in sputum in the preceding 6 months in the case of non-CF patients, and 2 years in the case of CF patients.
- •Current infectious exacerbation requiring treatment with intravenous antibiotics, suitable to be managed on OPAT
- •Productive of sputum
排除标准
- •Unable to consent
- •Current pregnancy (as confirmed by urine beta-HCG) or partner who is currently pregnant
- •Current breastfeeding
- •Not appropriate for OPAT (as determined by treating clinician)
- •Estimated CrCl < 50mL/min
- •History of hypersensitivity reaction to piperacillin/tazobactam or members of the cephalosporin class of antibiotics
- •Unable to expectorate
研究者
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