Trans Thoracic Ultrasound to Assess Diaphragmatic Function in Stable COPD Versus Bronchial Asthma.

Not Applicable

Not yet recruiting

• Conditions: Diaphragm
• Interventions: Device: ultrasound

• Registration Number: NCT06348745
• Lead Sponsor: Assiut University

Brief Summary

* Assessment of diaphragmatic function (excursion, thickness variation, thickness ratio) in COPD and bronchial asthma patients.

* Assessment of presence of correlation between diaphragmatic dysfunction and pulmonary function.

* Assessment of possible association between diaphragmatic dysfunction and presence of reversibility in pulmonary function post bronchodilator.

Detailed Description

* Assessment of diaphragmatic function (excursion, thickness variation, thickness ratio) in COPD and bronchial asthma patients.

* Assessment of presence of correlation between diaphragmatic dysfunction and pulmonary function (FEV1/FVC).

* Assessment of possible association between diaphragmatic dysfunction and presence of reversibility in pulmonary function post bronchodilator (short acting B2 agonist)

Study Timeline

• Study First Submitted: 2024-02-28
• Study First Submitted QC: 2024-03-30
• Status Verified: 2024-04
• Study Start: 2024-04-01
• Study First Posted: 2024-04-05
• Last Update Submitted: 2024-04-05
• Last Update Posted: 2024-04-08
• Primary Completion: 2026-04-01
• Study Completion: 2026-05-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

Stable patients (not in exacerbation).

Exclusion Criteria

• Patients with comorbidities as cardiac, renal or hepatic diseases.
• Patients who have combined COPD and bronchial asthma.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
chronic obstructive pulmonary disease (COPD)	ultrasound	ultrasound to COPD patients to asses' diaphragmatic function.
bronchial asthma	ultrasound	ultrasound to bronchial asthma patients to asses' diaphragmatic function.

Primary Outcome Measures

Name	Time	Method
diaphragmatic function	2 years	Compare diaphragmatic function using ultrasound device by measuring diaphragmatic thickness in both stable COPD and bronchial asthma patients.

Secondary Outcome Measures

Name	Time	Method
pulmonary function .	2 years	assess the degree of effect of diaphragmatic dysfunction on pulmonary function measured by spirometry FEV1/FVC (forced expiratory volume1/ forced Vidal capacity )