Evaluation of Milk Fat Globule-Epidermal Growth Factor-Factor VIII Level in Gingival Crevicular Fluid and Saliva in Periodontal Disease and Health

Not Applicable

Completed

• Conditions: healty, gingivitis, periodontitis; gingivitis; saliva; gingival crevicular fluid; IL- 1β; Mfg- E8

• Registration Number: TCTR20180313005
• Lead Sponsor: none

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2017-01-01
• Study Start: 2018-03-13
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 74

Inclusion Criteria

1) mainly adult individuals with systemic healthy; 2) individuals with ≥20 natural teeth; 3) for patients with periodontitis, individuals with at least two quadrants of moderate-severe chronic periodontitis findings.

Exclusion Criteria

1) smoking; 2) systemic diseases may be reflected in the periodontium; 3) pregnancy; and 4) in the last 6 months, medication intake which may affect the periodontium or receiving periodontal treatment.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
observe the relationship between periodontal diseases and levels of Mfg-E8 after all samples have been collected ELÄ°SA

Secondary Outcome Measures

Name	Time	Method
Observation of IL-1 beta correlation with Mfg-E8 after all samples have been collected ELÄ°SA