Implementation and Effectiveness of the BJC-Pink and Pearl Project on Lung Cancer Screening

Recruiting

• Conditions: Lung Cancer; Cancer of the Lung

• Registration Number: NCT06898333
• Lead Sponsor: Washington University School of Medicine

Brief Summary

The investigators proposal is ripe for executing as the investigators seek to leverage this "natural experiment" initiated by the BJC health system to evaluate the effectiveness of the Pink \& Pearl Campaign as an implementation strategy to promote lung cancer screening (LCS) uptake among LCS-eligible women undergoing mammography at BJC West County. This evaluation is grounded in the Integrated Screening Action Model that depicts individual- and environmental-level influences on the screening behavior process. Using an explanatory sequential mixed methods design, which combines both quantitative and qualitative approaches, the research questions and specific aims for this proposal are to: a) evaluate the baseline prevalence of LCS among LCS-eligible women; b) assess whether the Pink \& Pearl Campaign increases referrals and uptake/ completion of LCS among LCS-eligible women undergoing screening mammography; and c) evaluate individual and environmental factors influencing LCS uptake, and implementation outcomes of the campaign. These implementation outcomes will help identify whether the campaign was put in place successfully or not. This proposal will inform strategies for integrating cancer screening programs to improve poorly performing programs like LCS.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2025-03-20
• Study First Submitted QC: 2025-03-20
• Study First Posted: 2025-03-27
• Status Verified: 2025-05
• Study Start: 2025-05-08
• Last Update Submitted: 2025-05-08
• Last Update Posted: 2025-05-14
• Primary Completion: 2026-11-30
• Study Completion: 2027-05-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 279

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Prevalence of LCS-eligible women who opt-in to, and successfully, complete LCS mammography and opt-in to lung cancer screening	At baseline
Number of women screened for LCS	At 6 months
Feasibility of Pink and Pearl project	At 6 months	Feasibility is defined as the extent to which the strategy is suitable for routine use in a setting.; Information on the feasibility of the Pink and Pearl campaign from healthcare providers will be collected using in-depth interviewing.
Acceptability of Pink and Pearl project	At 6 months	Acceptability is defined as the perception that the strategy is agreeable or satisfactory.; Information on the acceptability of the Pink and Pearl campaign from healthcare providers will be collected using in-depth interviewing.
Appropriateness of Pink and Pearl project	At 6 months	Appropriateness is defined as the perceived fit, relevance, or compatibility of the strategy or practice for a given setting.; Information on the appropriateness of the Pink and Pearl campaign from healthcare providers will be collected using in-depth interviewing.

Secondary Outcome Measures

Name	Time	Method
Median time to lung cancer screening	Through completion of follow-up (estimated to be 1 year)
Number of women who have a positive lung radiology screening	Through completion of follow-up (estimated to be 1 year)
Rate of follow-up for a positive screening examination	Through completion of follow-up (estimated to be 1 year)
False positive rates	Through completion of follow-up (estimated to be 1 year)
Invasive intervention rate	Through completion of follow-up (estimated to be 1 year)	Invasive interventions are considered percutaneous cytologic examination or biopsy, bronchoscopy, surgical procedure mediastinoscopy/otmy, and thorascopy/otmy.
Cancer yield rate	Through completion of follow-up (estimated to be 1 year)
Adverse event rate for screening	Through completion of follow-up (estimated to be 1 year)
Number of women with varying Stage (1-4) findings in the lung screening radiology report.	Through completion of follow-up (estimated to be 1 year)	Histologic type (Bronchioloalveolar carcinoma, adenocarcinoma, squamous-cell carcinoma, large-cell carcinoma, non-small-cell carcinoma or other, small-cell carcinoma, carcinoid).
Cause of death	Through completion of follow-up (estimated to be 1 year)	Neoplasm of bronchus and lung, other neoplasm, cardiovascular illness, respiratory illness, complications of medical or surgical care, other.

Trial Locations

Locations (1)

Barnes-Jewish Hospital West County; 🇺🇸 Creve Coeur, Missouri, United States