Mechanisms of Neural Mobilization in the Treatment of Chronic Pain
Trial Snapshot
- Phase
- Phase 1
- Status
- Completed
- Sponsor
- University of Florida
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- thermal and pressure pain sensitivity
Study Overview
Brief Summary
The purpose of this study was to determine the effect of a manual therapy technique (neural mobilization) on measures of clinical pain and function, experimental pain sensitivity, and on the function of the median nerve in individuals with carpal tunnel syndrome. The investigators hypothesized that individuals receiving a neural mobilization technique known to directly stress the median nerve would demonstrate greater improvements in clinical pain and function, experimental pain sensitivity, and median nerve function than those receiving a sham technique.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 70 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •18 to 70 years of age
- •signs and symptoms of carpal tunnel syndrome for greater than 12 weeks
Exclusion Criteria
- •non english speaking
- •prior surgery for carpal tunnel syndrome
- •systemic condition known to affect sensation
- •chronic pain condition other than carpal tunnel syndrome
Arms & Interventions
neural mobilization
manual therapy technique known to directly stress the median nerve
Intervention: neural mobilization (Procedure)
sham neural mobilization
manual therapy technique known to directly stress the median nerve without any stimulation.
Intervention: sham neural mobilization (Procedure)
Healthy Controls
People without carpal tunnel syndrome for comparison
Intervention: healthy controls (Other)
Outcomes
Primary Outcomes
thermal and pressure pain sensitivity
Time Frame: immediate effect
Secondary Outcomes
- wrist range of motion(3 weeks)
- clinical pain(3 weeks)
- median nerve function(3 weeks)
- self report of disability(3 weeks)
- grip strength(3 weeks)