POSTOPERATIVE PAIN MANAGEMENT USING BUPIVACAINE AFTER MANDIBULAR ORTHOGNATHIC SURGERY: A TRIPLE-BLINDED RANDOMIZED CONTROLLED CLINICAL TRIA

Phase 4

Completed

• Conditions: Postoperative pain after mandibular orthognathic surgery; postoperative pain, Bupivacaine, BSSRO, orthognathic surgery, pain control

• Registration Number: TCTR20200128007
• Lead Sponsor: Faculty of Dentistry, Mahidol University, Thailand

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-01-28
• Study Completion: 2021-03-15
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 28

Inclusion Criteria

1. American Society of Anesthesiologist (ASA): class I and II
2. Patients undergoing Bilateral Sagittal Split Osteotomy (BSSRO) of mandible
only without complication.
- Mandibular advancement or setback

Exclusion Criteria

1. All the patients with any history of allergy to local anesthetics, opioid, NSAID or any of the
medications being administered.
2. Patients with a history of narcotic or alcohol abuse.
3. Patients with a history of chronic debilitating disease.
4. Chronic opioid analgesic use.
5. Pregnancy and lactating mother.
6. Patients undergoing both jaw surgery (lefort 1 + BSSRO) or Lefort 1 only

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Postoperative analgesic efficacy of bupivacaine 24 hour Numeric Rating Scale (NRS) for pain,Amount of rescue medicine needed for postoperative pain control 24 hour total milligram

Secondary Outcome Measures

Name	Time	Method
Duration of postoperative analgesia 24 hours time between the injection of solution to the time when patient asks for first dose rescue medicine,patient satisfaction 24 hours Verbal Rating Score (VRS)