Cardiovascular disease manifestations with special emphasis on myocarditis-in moderate to severe COVID-19 patients undergoing treatment in the ccu of a tertiary care hospital in West Bengal India
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 382
- Locations
- 1
- Primary Endpoint
- 1. Need for mechanical ventilation
Study Overview
Brief Summary
Hospitalized patients admitted with fever, cough, sore throat and/or dyspnoea who will be tested positive for SARS-COV-2 will be included in our study and will be matched based on their age and gender with patients admitted with similar symptoms who will be tested negative for SARS-COV-2. The electronic medical charts of the study subjects will be reviewed and relevant demographic, clinical, laboratory and imaging findings will be de-identified and recorded. Demographic characteristics including age at the time of diagnosis, gender, race and BMI will be collected. Past medical history including CAD, heart failure with reduced or preserved ejection fraction, AF, hypertension, dyslipidemia, DM, smoking status as well as home medication will be abstructed. The name and daily dose of ACE inhibitors or ARB will be recorded. Laboratory values including cardiac enzymes, electrolytes, Haemoglobin and creatinine will be collected. Available EKG and TTEs will be individually reviewed by an independent cardiovascular disease fellow or faculty member. Finally clinical outcomes including need for mechanical ventilation, length of intensive care unit stay, length of hospitalization, arrhythmias, cardiac arrest and in hospital mortality will be abstructed from the electronic charts.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 18.00 Year(s) to 80.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Age more than 18 years
- •Laboratory confirmed COVID-19 patients
- •SpO2 less than 94%
- •Patients on different modalities of oxygen therapy
- •Patients with radiologically confirmed pneumonia
- •ARDS or Acute Respiratory Failure Control
- •COVID-19 RTPCR negative 3.
Exclusion Criteria
- •Moribund patient with septicemia with or without multiorgan dysfunction
- •Patient unwilling to participate in the study.
Outcomes
Primary Outcomes
1. Need for mechanical ventilation
Time Frame: Within 28 days from CCU admission
3. Length of hospitalization
Time Frame: Within 28 days from CCU admission
2. Length of CCU stay
Time Frame: Within 28 days from CCU admission
4. Incidence of arrhythmia, cardiac arrest during CCU stay
Time Frame: Within 28 days from CCU admission
5. Final outcome-discharge or death
Time Frame: Within 28 days from CCU admission
Secondary Outcomes
- All cause mortality(Within 28 days from CCU admission)
