Cardiovascular disease manifestations with special emphasis on myocarditis-in moderate to severe COVID-19 patients undergoing treatment in the ccu of a tertiary care hospital in West Bengal India
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 382
- 试验地点
- 1
- 主要终点
- 1. Need for mechanical ventilation
研究概览
简要总结
Hospitalized patients admitted with fever, cough, sore throat and/or dyspnoea who will be tested positive for SARS-COV-2 will be included in our study and will be matched based on their age and gender with patients admitted with similar symptoms who will be tested negative for SARS-COV-2. The electronic medical charts of the study subjects will be reviewed and relevant demographic, clinical, laboratory and imaging findings will be de-identified and recorded. Demographic characteristics including age at the time of diagnosis, gender, race and BMI will be collected. Past medical history including CAD, heart failure with reduced or preserved ejection fraction, AF, hypertension, dyslipidemia, DM, smoking status as well as home medication will be abstructed. The name and daily dose of ACE inhibitors or ARB will be recorded. Laboratory values including cardiac enzymes, electrolytes, Haemoglobin and creatinine will be collected. Available EKG and TTEs will be individually reviewed by an independent cardiovascular disease fellow or faculty member. Finally clinical outcomes including need for mechanical ventilation, length of intensive care unit stay, length of hospitalization, arrhythmias, cardiac arrest and in hospital mortality will be abstructed from the electronic charts.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)(—)
- 性别
- All
入选标准
- •Age more than 18 years
- •Laboratory confirmed COVID-19 patients
- •SpO2 less than 94%
- •Patients on different modalities of oxygen therapy
- •Patients with radiologically confirmed pneumonia
- •ARDS or Acute Respiratory Failure Control
- •COVID-19 RTPCR negative 3.
排除标准
- •Moribund patient with septicemia with or without multiorgan dysfunction
- •Patient unwilling to participate in the study.
结局指标
主要结局
1. Need for mechanical ventilation
时间窗: Within 28 days from CCU admission
3. Length of hospitalization
时间窗: Within 28 days from CCU admission
2. Length of CCU stay
时间窗: Within 28 days from CCU admission
4. Incidence of arrhythmia, cardiac arrest during CCU stay
时间窗: Within 28 days from CCU admission
5. Final outcome-discharge or death
时间窗: Within 28 days from CCU admission
次要结局
- All cause mortality(Within 28 days from CCU admission)
