Outpatient Clinic of Alexandria University Teaching Hospital, Egypt
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 9
- 试验地点
- 2
- 主要终点
- Evaluation of the soft tissue wound's healing
研究概览
简要总结
the study evaluated the one stage endoscopic middle meatal antrostomy (EMMA) technique with the application of a platelet rich fibrin membrane (PRF) for Oroantral Fistula (OAF) closure and relief of maxillary sinusitis.
详细描述
This study was conducted on nine eligible patients who complained of OAF with odontogenic sinusitis. Oral fistulectomy was done with proper curettage. Then, EMMA was performed with simultaneous closure of the OAF by application of PRF membrane and covering it with an acrylic splint. Patients were clinically evaluated for closure of the OAF after 14th days postoperatively, relief of the symptoms, and assessment of the pain level. Also, measurement of the size of the bone defect with the aid of computed tomography (CT) preoperatively and 24th weeks postoperatively.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •1 - Adult patients between the ages of 20-60 years. 2- Patients who were suffering from chronic fistula that occurred after the extraction of upper posterior teeth
排除标准
- •patients who have any systemic disease that contraindicates any intervention under general anesthesia (e.g., coronary artery disease).
- •OAF that occurred as a result of other causes (e.g., cyst,and trauma)
研究组 & 干预措施
closure of the OAF with PRF application
This study was conducted on 9 patients. application of PRF membrane
干预措施: closure by PRF membrane (Procedure)
结局指标
主要结局
Evaluation of the soft tissue wound's healing
时间窗: 1st, 7th, and14 days postoperatively
closure of the fistula using the Clinical Healing Score (CHS). CHS: score ranging from 0-5
次要结局
- Secondary radiographic outcomes, assessment of bone formation(24 weeks postoperatively)